Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 2/20 | 0.56 |
| ▸ | PRKG1 | Q13976 | 2/20 | 0.56 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | USP5 | P45974 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17530252 | 0.85 | CTSS (0.53) | ROCK2PRKG1CHRM4DRD2CTSK | |
| Hydrochloric Acid SCHEMBL30206729 | 0.77 | DRD2 (0.56) | ROCK2PRKG1CHRM4DRD2USP5 | |
| SCHEMBL17530195 | 0.77 | PLK4 (0.47) | PRKG1 | |
| SCHEMBL17530199 | 0.76 | CTSS (0.48) | DRD2CTSK | |
| SCHEMBL2637036 | 0.74 | DRD2 (0.59) | ROCK2PRKG1CHRM4DRD2USP5 | |
| SCHEMBL14590572 | 0.74 | QDPR (0.61) | ROCK2PRKG1CHRM4DRD2USP5 | |
| SCHEMBL7659138 | 0.73 | DRD2 (0.69) | CHRM4DRD2USP5CCR2 | |
| SCHEMBL17529983 | 0.73 | CTSS (0.57) | ROCK2PRKG1CHRM4POLBCTSK | |
| SCHEMBL27382202 | 0.72 | DRD2 (0.57) | ROCK2PRKG1CHRM4DRD2USP5 | |
| Hydrochloric Acid SCHEMBL11816492 | 0.72 | DRD2 (0.61) | ROCK2PRKG1CHRM4DRD2USP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016027284-A2 | PIPERIDINE UREAS AS CATHEPSIN CYSTEINE PROTEASE INHIBITORS | ALKEM LABORATORIES LTD. (IN) | 2016-02-25 | — | — | WO | disclosed |