SCHEMBL17530337

SCHEMBL17530337

CC(C)(C)OC(=O)N1CCCC(c2ccc(S(C)(=O)=O)cc2)C1

nearest known ligand 0.62

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 19/20 0.62
PDE4B Q07343 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4519083 0.86 GPR119 (0.76) GPR119
SCHEMBL20748135 0.85 PDE4B (0.53) GPR119PDE4B
SCHEMBL18509294 0.85 GPR119 (0.54) GPR119PDE4B
SCHEMBL28301552 0.85 PDE4B (0.53) GPR119PDE4B
SCHEMBL1673620 0.84 FPR2 (0.55) PDE4B
SCHEMBL12279408 0.84 MEN1 (0.57) PDE4B
SCHEMBL1421908 0.84 PDE4B (0.52) GPR119PDE4B
SCHEMBL22810473 0.84 PDE4B (0.52) PDE4B
SCHEMBL28943526 0.84 FPR2 (0.55) PDE4B
SCHEMBL1422394 0.84 PDE4B (0.52) GPR119PDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016027284-A2 PIPERIDINE UREAS AS CATHEPSIN CYSTEINE PROTEASE INHIBITORS ALKEM LABORATORIES LTD. (IN) 2016-02-25 WO disclosed