Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | IDE | P14735 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.35 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17530805 | 0.90 | CLK1 (0.38) | ALDH1A1MAPTSMN1; SMN2PIK3R2 | |
| SCHEMBL17530781 | 0.88 | ALDH1A1 (0.42) | ALDH1A1MAPTLMNAKDM4EGAA | |
| SCHEMBL17530791 | 0.85 | STK4 (0.40) | ALDH1A1SOS1 | |
| SCHEMBL715265 | 0.85 | MAPT (0.42) | MAPTLMNAHTTTP53MAPK1 | |
| SCHEMBL715264 | 0.85 | MAPT (0.42) | MAPTLMNAHTTTP53MAPK1 | |
| SCHEMBL17530771 | 0.83 | OPRK1 (0.40) | KDM4ETP53CNR2 | |
| SCHEMBL17530823 | 0.83 | OPRK1 (0.40) | KDM4ETP53CNR2 | |
| SCHEMBL17530783 | 0.82 | KDM4E (0.38) | ALDH1A1MAPTLMNAKDM4EHTT | |
| SCHEMBL17530769 | 0.81 | MAPT (0.45) | ALDH1A1MAPTLMNAKDM4ETP53 | |
| SCHEMBL17530834 | 0.80 | IDH1 (0.41) | SOS1PIK3R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403847-B1 | TRIAZINE DERIVATIVES AS KINASE INHIBITORS | UCB BIOPHARMA SPRL (BE) | 2016-03-02 | — | — | EP | claimed |