Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.74 |
| ▸ | CTSS | P25774 | 4/20 | 0.60 |
| ▸ | CTSL | P07711 | 1/20 | 0.57 |
| ▸ | CTSB | P07858 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22236516 | 0.92 | CTSK (0.68) | CTSKCTSSCTSLCTSB | |
| SCHEMBL17133745 | 0.91 | CTSK (0.64) | CTSKCTSSCTSLCTSB | |
| SCHEMBL17146997 | 0.91 | CTSK (0.64) | CTSKCTSSCTSLCTSB | |
| SCHEMBL17133720 | 0.90 | CTSK (0.63) | CTSKCTSSCTSLCTSB | |
| SCHEMBL15083612 | 0.90 | CTSK (0.63) | CTSKCTSSCTSLCTSB | |
| SCHEMBL18546494 | 0.87 | CTSK (0.64) | CTSKCTSSCTSLCTSB | |
| SCHEMBL18546605 | 0.87 | CTSK (0.64) | CTSKCTSSCTSLCTSB | |
| SCHEMBL25884513 | 0.87 | CTSK (0.64) | CTSKCTSSCTSLCTSB | |
| SCHEMBL26087282 | 0.86 | CTSK (0.64) | CTSKCTSSCTSLCTSB | |
| SCHEMBL23218022 | 0.86 | CTSS (0.63) | CTSKCTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9388123-B2 | LSD1-selective inhibitor having lysine structure | KYOTO UNIVERSITY (JP) | 2016-07-12 | — | — | US | disclosed |
| US-20160039748-A1 | LSD1-SELECTIVE INHIBITOR HAVING LYSINE STRUCTURE | KYOTO UNIVERSITY (JP) | 2016-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160039748-A1 | LSD1-SELECTIVE INHIBITOR HAVING LYSINE STRUCTURE | KDM1A, DOT1L, KDM1B | CTSK 2479/4885CTSS 2069/4885CTSL 3512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.