Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 6/20 | 0.63 |
| ▸ | CTSK | P43235 | 6/20 | 0.63 |
| ▸ | CTSB | P07858 | 2/20 | 0.59 |
| ▸ | CTSL | P07711 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 1/20 | 0.52 |
| ▸ | AKT1 | P31749 | 1/20 | 0.52 |
| ▸ | REN | P00797 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 1/20 | 0.51 |
| ▸ | BACE1 | P56817 | 3/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17614472 | 1.00 | CTSS (0.63) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL23218021 | 1.00 | CTSS (0.63) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL17277928 | 0.91 | CTSK (0.60) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL8574599 | 0.90 | CTSS (0.61) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL8574604 | 0.90 | CTSS (0.61) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL18546494 | 0.89 | CTSK (0.64) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL25884513 | 0.89 | CTSK (0.64) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL18546605 | 0.89 | CTSK (0.64) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL22236516 | 0.89 | CTSK (0.68) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL24648945 | 0.89 | CTSK (0.50) | CTSSCTSKCTSBCTSLREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022076905-A1 | ALK5 INHIBITORS, CONJUGATES, AND USES THEREOF | SILVERBACK THERAPEUTICS, INC. (US) | 2022-04-14 | — | — | WO | disclosed |
| WO-2021072330-A1 | GALNAC-TGFBR1 INHIBITOR CONJUGATES FOR THE TREATMENT OF LIVER DISEASES | SILVERBACK THERAPEUTICS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |