SCHEMBL17533175

SCHEMBL17533175

NCC(Nc1ccccc1)c1ccc(-c2cccc(-c3ccccc3)c2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.49
CHRNA4 P43681 1/20 0.49
RPS6KA5 O75582 2/20 0.42
AKT1 P31749 2/20 0.42
GSK3B P49841 2/20 0.42
NEK4 P51957 2/20 0.42
PRKCD Q05655 2/20 0.42
PRKG2 Q13237 2/20 0.42
ROCK1 Q13464 2/20 0.42
PRKG1 Q13976 2/20 0.42
PKN2 Q16513 2/20 0.42
CLK4 Q9HAZ1 2/20 0.42
MAPK13 O15264 1/20 0.42
DYRK3 O43781 1/20 0.42
ROCK2 O75116 1/20 0.42
PRKD3 O94806 1/20 0.42
MAP4K4 O95819 1/20 0.42
CHEK2 O96017 1/20 0.42
PRKCG P05129 1/20 0.42
CDK1 P06493 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7093029 0.82 TAAR1 (0.50) CHRNB2CHRNA4RPS6KA5AKT1GSK3B
SCHEMBL27220939 0.75 CHRNB2 (0.53) CHRNB2CHRNA4RPS6KA5AKT1GSK3B
SCHEMBL11781440 0.74 ALDH1A1 (0.55) RPS6KB1
Hydrochloric Acid SCHEMBL9001664 0.73 CHRNB2 (0.55) CHRNB2CHRNA4RPS6KA5AKT1GSK3B
SCHEMBL29157126 0.72 CTSA (0.51) MMP8MMP14CA14
SCHEMBL8790210 0.71 MAPT (0.56) CHRNB2CHRNA4TAAR1
SCHEMBL27220938 0.71 CHRNB2 (0.49) CHRNB2CHRNA4RPS6KA5AKT1GSK3B
SCHEMBL31147717 0.71 MAOA (0.40) CHRNB2CHRNA4ROCK1ROCK2CA2
SCHEMBL11203104 0.68 HRH1 (0.54) RPS6KB1TAAR1
SCHEMBL10780978 0.68 ALDH1A1 (0.61) RPS6KB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016028110-A1 A PLURALITY OF HOST MATERIALS AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2016-02-25 WO disclosed