Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.48 |
| ▸ | HTR3B | O95264 | 2/20 | 0.48 |
| ▸ | HTR3A | P46098 | 2/20 | 0.48 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.48 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.48 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.48 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.48 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | NOS1 | P29475 | 5/20 | 0.46 |
| ▸ | NOS3 | P29474 | 4/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9541668 | 0.80 | KMT2A (0.50) | KMT2AMEN1HTR3EHTR3BHTR3A | |
| SCHEMBL9367211 | 0.78 | ATM (0.65) | KMT2AMEN1HTR3EHTR3BHTR3A | |
| SCHEMBL13818953 | 0.78 | ATM (0.65) | KMT2AMEN1HTR3EHTR3BHTR3A | |
| SCHEMBL9367215 | 0.78 | ATM (0.65) | KMT2AMEN1HTR3EHTR3BHTR3A | |
| SCHEMBL16513121 | 0.77 | ATM (0.46) | ATMCYP2C19MAPTGRIN1GRIN2B | |
| SCHEMBL9834835 | 0.77 | ATM (0.46) | ATMLMNAALOX15CYP2C19MAPT | |
| SCHEMBL7331705 | 0.77 | ATM (0.46) | ATMLMNAALOX15CYP2C19MAPT | |
| SCHEMBL6369259 | 0.77 | CTSL (0.51) | KMT2AMEN1HTR3EHTR3BHTR3A | |
| SCHEMBL23597427 | 0.75 | ATM (0.50) | KMT2AMEN1NOS1NOS3ATM | |
| SCHEMBL11368072 | 0.74 | MEN1 (0.44) | KMT2AMEN1HTR3EHTR3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016028110-A1 | A PLURALITY OF HOST MATERIALS AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME | ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) | 2016-02-25 | — | — | WO | disclosed |