SCHEMBL9541668

SCHEMBL9541668

OCC(=Nc1ccccc1)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.50
MEN1 O00255 2/20 0.50
ATM Q13315 1/20 0.45
HTR3E A5X5Y0 2/20 0.44
HTR3B O95264 2/20 0.44
HTR3A P46098 2/20 0.44
HTR3D Q70Z44 2/20 0.44
HTR3C Q8WXA8 2/20 0.44
SLC22A2 O15244 2/20 0.44
SLC22A1 O15245 1/20 0.44
SLC22A3 O75751 1/20 0.44
PLAU P00749 1/20 0.44
NOS1 P29475 5/20 0.43
NOS3 P29474 4/20 0.43
ESR1 P03372 1/20 0.42
ESR2 Q92731 1/20 0.42
MAPT P10636 3/20 0.41
LMNA P02545 2/20 0.39
ALOX15 P16050 2/20 0.39
CYP1A2 P05177 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17533331 0.80 KMT2A (0.54) KMT2AMEN1ATMHTR3EHTR3B
SCHEMBL9367211 0.80 ATM (0.65) KMT2AMEN1ATMHTR3EHTR3B
SCHEMBL9367215 0.80 ATM (0.65) KMT2AMEN1ATMHTR3EHTR3B
SCHEMBL13818953 0.80 ATM (0.65) KMT2AMEN1ATMHTR3EHTR3B
SCHEMBL6369259 0.78 CTSL (0.51) KMT2AMEN1ATMHTR3EHTR3B
SCHEMBL23597427 0.77 ATM (0.50) KMT2AMEN1ATMNOS1NOS3
SCHEMBL2470468 0.76 ATM (0.48) KMT2AMEN1ATMMAPTALOX15
SCHEMBL11368072 0.75 MEN1 (0.44) KMT2AMEN1ATMHTR3EHTR3B
SCHEMBL11368075 0.75 MEN1 (0.44) KMT2AMEN1ATMHTR3EHTR3B
SCHEMBL10592550 0.74 ATM (0.46) ATMMAPTGRIN1GRIN2BGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993014053-A1 PROCESS FOR THE PREPARATION OF 1,3,5-TRIS(4'-HYDROXYARYL)BENZENE HOECHST CELANESE CORPORATION (US) 1993-07-22 WO disclosed
WO-1993014053-A1 PROCESS FOR THE PREPARATION OF 1,3,5-TRIS(4'-HYDROXYARYL)BENZENE HOECHST CELANESE CORPORATION (US) 1993-07-22 WO disclosed
US-4256627-A COMPRISING COMPLEXES OF POLYMERS HAVING UNITS CONTAINING ALKYLPIPERIDINE GROUPS AND NICKEL OR COBALT CARBOXYLATES OR ENOLATES CIBA-GEIGY CORPORATION (US) 1981-03-17 US disclosed