Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 15/20 | 0.48 |
| ▸ | CTSB | P07858 | 10/20 | 0.48 |
| ▸ | CTSL | P07711 | 9/20 | 0.48 |
| ▸ | CTSS | P25774 | 8/20 | 0.48 |
| ▸ | CTSV | O60911 | 1/20 | 0.48 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17533671 | 0.87 | CTSL (0.60) | CTSKCTSBCTSLCTSS | |
| SCHEMBL17533591 | 0.85 | CTSL (0.60) | CTSKCTSBCTSLCTSSCTSF | |
| SCHEMBL17533612 | 0.72 | CTSL (0.61) | CTSKCTSBCTSLCTSSCTSV | |
| SCHEMBL17514231 | 0.72 | CTSL (0.57) | CTSKCTSBCTSLCTSS | |
| SCHEMBL17533710 | 0.71 | CTSL (0.59) | CTSKCTSBCTSLCTSS | |
| SCHEMBL17533636 | 0.71 | CTSL (0.58) | CTSKCTSBCTSLCTSS | |
| SCHEMBL17533699 | 0.71 | CTSL (0.58) | CTSKCTSBCTSLCTSS | |
| SCHEMBL17533640 | 0.69 | CTSL (0.50) | CTSKCTSBCTSLCTSS | |
| SCHEMBL17533579 | 0.69 | PPARG (0.44) | CTSKCTSBCTSLCTSS | |
| SCHEMBL17514263 | 0.69 | GRN (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016027285-A2 | BICYCLIC HETEROARYL AMIDES AS CATHEPSIN CYSTEINE PROTEASE INHIBITORS | ALKEM LABORATORIES LTD. (IN) | 2016-02-25 | — | — | WO | disclosed |