Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 14/20 | 0.60 |
| ▸ | CTSB | P07858 | 8/20 | 0.44 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | CTSS | P25774 | 7/20 | 0.43 |
| ▸ | CTSK | P43235 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17533612 | 0.86 | CTSL (0.61) | CTSLCTSBCTSSCTSK | |
| SCHEMBL17514231 | 0.86 | CTSL (0.57) | CTSLCTSBCTSSCTSK | |
| SCHEMBL17533593 | 0.85 | CTSK (0.48) | CTSLCTSBCTSFCTSSCTSK | |
| SCHEMBL17533710 | 0.84 | CTSL (0.59) | CTSLCTSBPPARGCTSSCTSK | |
| SCHEMBL17533579 | 0.82 | PPARG (0.44) | CTSLCTSBPPARGCTSSCTSK | |
| SCHEMBL17533638 | 0.78 | CTSL (0.56) | CTSLCTSBPPARGCTSSCTSK | |
| SCHEMBL17533642 | 0.76 | CTSL (0.53) | CTSLCTSBCTSSCTSK | |
| SCHEMBL17514263 | 0.74 | GRN (0.54) | PPARG | |
| SCHEMBL17533634 | 0.74 | PPARG (0.38) | PPARG | |
| SCHEMBL17533607 | 0.73 | RORC (0.47) | CTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016027285-A2 | BICYCLIC HETEROARYL AMIDES AS CATHEPSIN CYSTEINE PROTEASE INHIBITORS | ALKEM LABORATORIES LTD. (IN) | 2016-02-25 | — | — | WO | disclosed |