Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 19/20 | 0.60 |
| ▸ | CTSS | P25774 | 11/20 | 0.59 |
| ▸ | CTSK | P43235 | 11/20 | 0.59 |
| ▸ | CTSB | P07858 | 4/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17533593 | 0.87 | CTSK (0.48) | CTSLCTSSCTSKCTSB | |
| SCHEMBL17514231 | 0.84 | CTSL (0.57) | CTSLCTSSCTSKCTSB | |
| SCHEMBL17533636 | 0.83 | CTSL (0.58) | CTSLCTSSCTSKCTSB | |
| SCHEMBL17533699 | 0.83 | CTSL (0.58) | CTSLCTSSCTSKCTSB | |
| SCHEMBL17514263 | 0.81 | GRN (0.54) | — | |
| SCHEMBL17514265 | 0.78 | TAS1R3 (0.47) | — | |
| SCHEMBL17533641 | 0.77 | CTSL (0.66) | CTSLCTSSCTSKCTSB | |
| SCHEMBL17533638 | 0.76 | CTSL (0.56) | CTSLCTSSCTSKCTSB | |
| SCHEMBL17533642 | 0.76 | CTSL (0.53) | CTSLCTSSCTSKCTSB | |
| SCHEMBL17533710 | 0.73 | CTSL (0.59) | CTSLCTSSCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016027285-A2 | BICYCLIC HETEROARYL AMIDES AS CATHEPSIN CYSTEINE PROTEASE INHIBITORS | ALKEM LABORATORIES LTD. (IN) | 2016-02-25 | — | — | WO | disclosed |