Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.36 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21805451 | 0.88 | CHRM1 (0.54) | PPARDFOLH1CHRM1AKR1A1CHRM3 | |
| SCHEMBL29159494 | 0.82 | TSHR (0.44) | PPARDFOLH1CHRM1AKR1A1CHRM3 | |
| SCHEMBL21804792 | 0.81 | PPARD (0.40) | PPARDTDP1MAPK1MAPTTSHR | |
| SCHEMBL27623719 | 0.81 | SLC1A3 (0.43) | PPARDFOLH1CHRM1AKR1A1CHRM3 | |
| SCHEMBL17504764 | 0.81 | FOLH1 (0.58) | FOLH1GRM3NAALAD2 | |
| SCHEMBL14561058 | 0.77 | FOLH1 (0.55) | PPARDFOLH1CHRM1AKR1A1CHRM3 | |
| SCHEMBL17533765 | 0.75 | FOLH1 (0.54) | FOLH1GRM3NAALAD2 | |
| SCHEMBL8967799 | 0.74 | TSHR (0.48) | PPARDTDP1MAPK1CA2MAPT | |
| SCHEMBL2233014 | 0.72 | CA2 (0.71) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL49001 | 0.72 | CHRM1 (0.76) | FOLH1CHRM1AKR1A1CHRM3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3853213-A1 | SHIELDING AGENTS AND THEIR USE | Endocyte, Inc. (US) | 2021-07-28 | — | — | EP | disclosed |
| WO-2020061293-A1 | SHIELDING AGENTS AND THEIR USE | ENDOCYTE, INC. (US) | 2020-03-26 | — | — | WO | disclosed |