SCHEMBL17535314

SCHEMBL17535314

Cc1nn(-c2cccnc2)c(F)c1N(CC(C)(C)C)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 3/20 0.39
CNR2 P34972 3/20 0.39
SLC16A3 O15427 1/20 0.38
SLC16A1 P53985 1/20 0.38
MYC P01106 1/20 0.37
WDR5 P61964 1/20 0.37
MAPK13 O15264 1/20 0.36
MAPK12 P53778 1/20 0.36
MAPK11 Q15759 1/20 0.36
MAPK14 Q16539 1/20 0.36
ALDH1A1 P00352 2/20 0.36
MAPT P10636 1/20 0.36
GRM1 Q13255 3/20 0.36
NR3C1 P04150 1/20 0.36
NAMPT P43490 2/20 0.35
POLB P06746 1/20 0.34
HSD11B1 P28845 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
GPR119 Q8TDV5 1/20 0.34
MEN1 O00255 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17535316 0.87 SMN1; SMN2 (0.42) CNR1CNR2SLC16A3SLC16A1MAPK13
SCHEMBL2690374 0.82 GRM1 (0.39) CNR1CNR2MYCWDR5ALDH1A1
SCHEMBL15362544 0.82 ALDH1A1 (0.40) CNR1CNR2SLC16A3SLC16A1MYC
SCHEMBL15362538 0.79 GPR119 (0.39) CNR1CNR2SLC16A3SLC16A1MYC
SCHEMBL17535312 0.77 GPR119 (0.42) CNR1CNR2SLC16A3SLC16A1MYC
SCHEMBL17535299 0.74 CNR1 (0.39) CNR1CNR2SLC16A3SLC16A1MYC
SCHEMBL14904612 0.73 PRSS1 (0.34) CNR1CNR2MYCWDR5MAPK14
SCHEMBL15975591 0.72 GRM1 (0.37) CNR1CNR2MYCWDR5ALDH1A1
SCHEMBL16269946 0.71 GAA (0.38) CNR1CNR2SLC16A3SLC16A1ALDH1A1
SCHEMBL2688872 0.71 SMN1; SMN2 (0.46) ALDH1A1MAPTGRM1NR3C1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9708288-B2 Pesticidal compositions and processes related thereto DOW AGROSCIENCES LLC (US) 2017-07-18 US disclosed
US-20160159766-A9 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2016-06-09 US disclosed
US-9282739-B2 Pesticidal compositions and processes related thereto DOW AGROSCIENCES LLC (US) 2016-03-15 US disclosed
US-20160060245-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2016-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160159766-A9 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO ACHE, DDT, PTMS CNR1 3239/4885CNR2 2557/4885SLC16A3 1551/4885
US-20160060245-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO ACHE, DDT, PTMS CNR1 3239/4885CNR2 2557/4885SLC16A3 1551/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.