Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | G6PD | P11413 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GALR3 | O60755 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5860401 | 1.00 | ALDH1A1 (0.59) | ALDH1A1HPGDMEN1KMT2ARAPGEF4 | |
| SCHEMBL4873588 | 0.93 | ALDH1A1 (0.68) | ALDH1A1HPGDMEN1KMT2ARAPGEF4 | |
| SCHEMBL14942254 | 0.88 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2ARAPGEF4HTT | |
| SCHEMBL15178042 | 0.88 | HPGD (0.67) | ALDH1A1HPGDMEN1KMT2ARAPGEF4 | |
| SCHEMBL1921510 | 0.88 | HPGD (0.67) | ALDH1A1HPGDMEN1KMT2ARAPGEF4 | |
| SCHEMBL5918700 | 0.88 | HPGD (0.67) | ALDH1A1HPGDMEN1KMT2ARAPGEF4 | |
| SCHEMBL260551 | 0.85 | ALDH1A1 (0.81) | ALDH1A1HPGDMEN1KMT2AHTT | |
| SCHEMBL10002565 | 0.83 | APP (0.55) | ALDH1A1HPGDMEN1KMT2ARAPGEF4 | |
| SCHEMBL10002566 | 0.83 | RAPGEF4 (0.44) | ALDH1A1HPGDMEN1KMT2ARAPGEF4 | |
| SCHEMBL9516537 | 0.80 | HPGD (0.78) | ALDH1A1HPGDMEN1KMT2ARAPGEF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655338-B1 | BENZOIMIDAZOLE DERIVATIVES FOR USE IN LIGHT-EMITTING DEVICES | NITTO DENKO CORP (JP) | 2016-02-24 | — | — | EP | disclosed |