SCHEMBL260551

SCHEMBL260551

Cc1ccc(-c2ccc(Br)cc2)cc1

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.81
MAPK1 P28482 1/20 0.55
ACHE P22303 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
CYP2A6 P11509 1/20 0.50
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48
CYP2C19 P33261 1/20 0.48
HTT P42858 1/20 0.48
NPC1 O15118 3/20 0.45
RAB9A P51151 3/20 0.45
MAOB P27338 1/20 0.45
APP P05067 1/20 0.45
PAX8 Q06710 1/20 0.45
GAA P10253 2/20 0.43
AHR P35869 2/20 0.42
CA12 O43570 1/20 0.42
CA2 P00918 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15678841 0.92 ALDH1A1 (0.68) ALDH1A1MAPK1ACHETDP1CYP2A6
SCHEMBL13072157 0.92 ALDH1A1 (0.68) ALDH1A1MAPK1ACHETDP1CYP2A6
SCHEMBL808 0.90
SCHEMBL8158529 0.87
Ammonia Solution, Strong SCHEMBL4261771 0.87
Hydrochloric Acid SCHEMBL29138708 0.87
Fluoride SCHEMBL27331410 0.87 ALDH1A1 (0.93) ALDH1A1MAPK1ACHETDP1CYP2A6
Ethane SCHEMBL28852928 0.87 ALDH1A1 (0.93) ALDH1A1MAPK1ACHETDP1CYP2A6
Phosphine SCHEMBL22129226 0.87
SCHEMBL27475913 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114085300-B Modified polybutadiene resin and preparation method and application thereof 南亚新材料科技股份有限公司 2023-09-15 CN claimed
CN-114085300-A Modified polybutadiene resin and preparation method and application thereof 南亚新材料科技股份有限公司 2022-02-25 CN claimed
CN-119977820-A Benzo-polycyclic substituted triarylamine compound, application thereof and organic electroluminescent device 合肥鼎材科技有限公司 2025-05-13 CN disclosed
CN-115745833-B Preparation method of 4-alkyl-4' -cyanobiphenyl 宁夏中星显示材料有限公司 2024-07-05 CN disclosed
CN-110997871-B Liquid crystal compound 默克专利股份有限公司 2024-04-30 CN disclosed
CN-117551023-A Preparation method and application of N-thio-phenyl phthalimide compound 太原理工大学 2024-02-13 CN disclosed
US-20230340348-A1 CO2-PHILIC CROSSLINKED POLYETHYLENE GLYCOL-BASED MEMBRANES FOR ACID AND SOUR GAS SEPARATIONS SAUDI ARABIAN OIL COMPANY (SA) 2023-10-26 US disclosed
US-11778901-B2 Organic electroluminescent material and organic electroluminescent device comprising same SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-10-03 US disclosed
US-11767297-B2 Compounds for inhibiting TNIK and medical uses thereof KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2023-09-26 US disclosed
US-11767297-B2 Compounds for inhibiting TNIK and medical uses thereof KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2023-09-26 US disclosed
CN-114085300-B Modified polybutadiene resin and preparation method and application thereof 南亚新材料科技股份有限公司 2023-09-15 CN disclosed
US-6525199-B1 Ring coupling, reduction and deprotecting; synthesis of compounds for alleviation and treatment of symptoms due to ischemic diseases SUNTORY LIMITED (JP) 2003-02-25 US disclosed
US-6455549-B1 ANTIEPILEPTIC, ANTIISCHEMIC, AND ANTIMIGRAINE AGENTS; CALCIUM OVELOAD SUPPRESSANTS SUNTORY LIMITED (JP) 2002-09-24 US disclosed
US-6407099-B1 SUPPRESSING CYTOTOXIC CALCIUM OVERLOAD AND LIPID PEROXIDATION; ANTIEPILEPTIC, ANTIISCHEMIC, AND ANTIEDEMIC AGENTS; BRAIN, NERVOUS SYSTEM, AND CARDIOVASCULAR DISORDERS SUNTORY LIMITED (JP) 2002-06-18 US disclosed
EP-1157842-A1 INK JET PRINTER HEAD AND PRODUCTION METHOD THEREOF, AND POLYCYCLIC THIOL COMPOUND SEIKO EPSON CORPORATION (JP) 2001-11-28 EP disclosed
EP-1138678-A2 Process for making N-((4-phenyl) methylphenyl) piperazines SUNTORY LIMITED (JP) 2001-10-04 EP disclosed
EP-0867183-A1 ARYLPIPERIDINOL AND ARYLPIPERIDINE DERIVATIVES AND DRUGS CONTAINING THE SAME SUNTORY LIMITED (JP) 1998-09-30 EP disclosed
EP-0391212-A2 Process for preparing bifunctional Z-stilbene compounds, new bifunctional Z-stilbene compounds and their use for preparing polymers BAYER AG (DE) 1990-10-10 EP disclosed
US-4179578-A Para-phenyl stilbene derivatives SANDOZ LTD. (CH) 1979-12-18 US disclosed
US-4032558-A PARA-PHENYL STILBENE DERIVATIVES SANDOZ LTD. (CH) 1977-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11767297-B2 Compounds for inhibiting TNIK and medical uses thereof TNNI3K, TNK1, TNIK ALDH1A1 4519/4885MAPK1 776/4885ACHE 1905/4885
US-11778901-B2 Organic electroluminescent material and organic electroluminescent device comprising same MAOA, AOC1, AOC2 ALDH1A1 67/4885MAPK1 789/4885ACHE 85/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.