Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | SLC5A2 | P31639 | 4/20 | 0.46 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SLC28A3 | Q9HAS3 | 2/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5569000 | 0.83 | SLC5A2 (0.52) | ACHESLC5A2SLC5A1TYRCA12 | |
| SCHEMBL9806206 | 0.83 | ACHE (0.69) | ACHESLC5A2SLC5A1TYRCA12 | |
| SCHEMBL10307314 | 0.83 | ACHE (0.69) | ACHESLC5A2SLC5A1TYRCA12 | |
| SCHEMBL15846873 | 0.83 | ACHE (0.69) | ACHESLC5A2SLC5A1TYRCA12 | |
| SCHEMBL7744549 | 0.83 | ACHE (0.69) | ACHESLC5A2SLC5A1TYRCA12 | |
| SCHEMBL15846875 | 0.83 | ACHE (0.69) | ACHESLC5A2SLC5A1TYRCA12 | |
| SCHEMBL29373662 | 0.80 | KDM1A (0.53) | ACHESLC5A2SLC5A1TYRPTGS1 | |
| SCHEMBL93243 | 0.74 | CA1 (0.54) | CA12CA1CA7CA9CA2 | |
| SCHEMBL17729111 | 0.73 | ACHE (0.48) | ACHESLC5A2SLC5A1TYRPTGS1 | |
| SCHEMBL13929525 | 0.73 | M6PR (0.46) | CA1CA9CA2GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8158372-B2 | Agonists of a bitter taste receptor and uses thereof | DEUTSCHES INSTITUT FÜR ERNÄHRUNGSFORSCHUNG POTSDAM-REHBRÜCKE (DE) | 2012-04-17 | — | — | US | disclosed |