Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.69 |
| ▸ | SLC5A2 | P31639 | 4/20 | 0.65 |
| ▸ | TYR | P14679 | 2/20 | 0.65 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.65 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.62 |
| ▸ | SLC28A3 | Q9HAS3 | 2/20 | 0.60 |
| ▸ | SNCA | P37840 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA7 | P43166 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9806206 | 1.00 | ACHE (0.69) | ACHESLC5A2TYRSLC5A1PTGS1 | |
| SCHEMBL15846875 | 1.00 | ACHE (0.69) | ACHESLC5A2TYRSLC5A1PTGS1 | |
| SCHEMBL10307314 | 1.00 | ACHE (0.69) | ACHESLC5A2TYRSLC5A1PTGS1 | |
| SCHEMBL15846873 | 1.00 | ACHE (0.69) | ACHESLC5A2TYRSLC5A1PTGS1 | |
| SCHEMBL1315789 | 0.88 | TYR (0.77) | ACHESLC5A2TYRSLC5A1PTGS1 | |
| SCHEMBL9179032 | 0.87 | ACHE (0.64) | ACHESLC5A2TYRSLC5A1PTGS1 | |
| SCHEMBL9218427 | 0.87 | ACHE (0.64) | ACHESLC5A2TYRSLC5A1PTGS1 | |
| SCHEMBL7088203 | 0.87 | ACHE (0.64) | ACHESLC5A2TYRSLC5A1PTGS1 | |
| SCHEMBL20056534 | 0.86 | ACHE (0.74) | ACHETYRPTGS1SNCAKDM4E | |
| SCHEMBL14120677 | 0.85 | TYR (0.66) | ACHESLC5A2TYRSLC5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11773127-B2 | Compounds and methods for treating bacterial infections | WASHINGTON UNIVERSITY (US) | 2023-10-03 | — | — | US | disclosed |
| US-11773127-B2 | Compounds and methods for treating bacterial infections | WASHINGTON UNIVERSITY (US) | 2023-10-03 | — | — | US | disclosed |
| US-11773127-B2 | Compounds and methods for treating bacterial infections | WASHINGTON UNIVERSITY (US) | 2023-10-03 | — | — | US | disclosed |
| US-20210171563-A1 | COMPOUNDS AND METHODS FOR TREATING BACTERIAL INFECTIONS | WASHINGTON UNIVERSITY (US) | 2021-06-10 | — | — | US | disclosed |
| US-20210171563-A1 | COMPOUNDS AND METHODS FOR TREATING BACTERIAL INFECTIONS | WASHINGTON UNIVERSITY (US) | 2021-06-10 | — | — | US | disclosed |
| WO-2001010877-A1 | C-GLYCOSIDE ANALOGS AND METHODS FOR THEIR PREPARATION AND USE | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2001-02-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210171563-A1 | COMPOUNDS AND METHODS FOR TREATING BACTERIAL INFECTIONS | MMP8, ELANE, MPO | ACHE 832/4885SLC5A2 864/4885TYR 273/4885 |
| US-11773127-B2 | Compounds and methods for treating bacterial infections | MMP8, ELANE, MPO | ACHE 832/4885SLC5A2 864/4885TYR 273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.