SCHEMBL1753707

SCHEMBL1753707

CC1(C)OB(c2ccc(-c3c4c(c(-c5ccccc5)c5ccccc35)-c3cccc5cccc-4c35)cc2)OC1(C)C

nearest known ligand 0.57

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 12/20 0.57
LPL P06858 11/20 0.57
P4HB P07237 1/20 0.39
KEAP1 Q14145 1/20 0.36
NFE2L2 Q16236 1/20 0.36
DGAT1 O75907 1/20 0.35
F11 P03951 2/20 0.35
F2 P00734 1/20 0.33
PRSS1 P07477 1/20 0.33
PRSS2 P07478 1/20 0.33
PRSS3 P35030 1/20 0.33
SNCA P37840 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13299967 0.90 LIPG (0.48) LIPGLPLP4HBDGAT1F11
SCHEMBL2515552 0.89 LIPG (0.46) LIPGLPLP4HB
SCHEMBL17014607 0.88 LIPG (0.55) LIPGLPLP4HBKEAP1NFE2L2
SCHEMBL21624614 0.85 LIPG (0.74) LIPGLPLP4HBKEAP1NFE2L2
SCHEMBL17701201 0.85 LIPG (0.74) LIPGLPLP4HBKEAP1NFE2L2
SCHEMBL21416280 0.83 LIPG (0.77) LIPGLPLP4HBKEAP1NFE2L2
SCHEMBL1509154 0.83 LIPG (0.77) LIPGLPLP4HBKEAP1NFE2L2
SCHEMBL9613217 0.83 LIPG (0.54) LIPGLPLP4HBSNCACA1
SCHEMBL12214091 0.83 LIPG (0.43) LIPGLPLP4HB
SCHEMBL21304574 0.81 LIPG (0.64) LIPGLPLP4HBKEAP1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120168739-A1 FLUORENE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE CANON KABUSHIKI KAISHA (JP) 2012-07-05 US disclosed
US-20120168739-A1 FLUORENE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE CANON KABUSHIKI KAISHA (JP) 2012-07-05 US disclosed
US-8158835-B2 Fluorene compound and organic electroluminescence device CANON KABUSHIKI KAISHA (JP) 2012-04-17 US disclosed
US-8158835-B2 Fluorene compound and organic electroluminescence device CANON KABUSHIKI KAISHA (JP) 2012-04-17 US disclosed
US-20090200919-A1 FLUORENE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE CANON KABUSHIKI KAISHA (JP) 2009-08-13 US disclosed
US-20090200919-A1 FLUORENE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE CANON KABUSHIKI KAISHA (JP) 2009-08-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120168739-A1 FLUORENE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE AFF1, LEF1, AFF2 LIPG 2072/4885LPL 1917/4885P4HB 3833/4885
US-20090200919-A1 FLUORENE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE AFF1, LEF1, AFF2 LIPG 2072/4885LPL 1917/4885P4HB 3833/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.