Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.63 |
| ▸ | MEN1 | O00255 | 7/20 | 0.63 |
| ▸ | MAPT | P10636 | 6/20 | 0.63 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.62 |
| ▸ | AHR | P35869 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | THRB | P10828 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | PPARG | P37231 | 1/20 | 0.59 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.55 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | ATP4A | P20648 | 2/20 | 0.54 |
| ▸ | ATP4B | P51164 | 2/20 | 0.54 |
| ▸ | AR | P10275 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21366458 | 0.86 | MEN1 (0.62) | KMT2AMEN1MAPTNR1I2AHR | |
| SCHEMBL21366050 | 0.84 | MAPT (0.60) | KMT2AMEN1MAPTNR1I2AHR | |
| SCHEMBL21366246 | 0.83 | MAPT (0.58) | KMT2AMEN1MAPTNR1I2AHR | |
| SCHEMBL21366326 | 0.83 | MAPT (0.58) | KMT2AMEN1MAPTNR1I2AHR | |
| SCHEMBL21366075 | 0.83 | MAPT (0.58) | KMT2AMEN1MAPTNR1I2AHR | |
| SCHEMBL17537647 | 0.83 | ADRA1A (0.50) | KMT2AMEN1MAPTNR1I2AHR | |
| SCHEMBL17537643 | 0.83 | NR4A2 (0.47) | KMT2AMEN1MAPTNR1I2AHR | |
| SCHEMBL17537646 | 0.83 | ATP4A (0.46) | KMT2AMEN1MAPTNR1I2AHR | |
| SCHEMBL21366112 | 0.82 | MAPT (0.57) | KMT2AMEN1MAPTNR1I2AHR | |
| SCHEMBL22462583 | 0.82 | MAPT (0.66) | KMT2AMEN1MAPTNR1I2AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016023106-A1 | BIS-INDOLE ALKALOIDS FOR USE IN THE TREATMENT OF INFECTIONS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2016-02-18 | — | — | WO | disclosed |