Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | ATP4A | P20648 | 5/20 | 0.47 |
| ▸ | ATP4B | P51164 | 5/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.41 |
| ▸ | F7 | P08709 | 1/20 | 0.40 |
| ▸ | F3 | P13726 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17537648 | 0.94 | ATP4A (0.42) | NR4A2ATP4AATP4BDYRK1AGSK3B | |
| SCHEMBL17537646 | 0.86 | ATP4A (0.46) | ATP4AATP4BMEN1KMT2AMAPT | |
| SCHEMBL17537647 | 0.86 | ADRA1A (0.50) | ATP4AATP4BGSK3BMEN1KMT2A | |
| SCHEMBL17537657 | 0.83 | KMT2A (0.63) | ATP4AATP4BMEN1KMT2AMAPT | |
| SCHEMBL17537645 | 0.81 | ADRA1A (0.46) | ATP4AATP4BGSK3BMEN1KMT2A | |
| SCHEMBL17537644 | 0.81 | ADRA1A (0.46) | ATP4AATP4BGSK3BMEN1KMT2A | |
| SCHEMBL17537630 | 0.80 | NR4A2 (0.50) | NR4A2ATP4AATP4BDYRK1AGSK3B | |
| SCHEMBL22585121 | 0.77 | NR4A2 (0.46) | NR4A2GSK3BMEN1KMT2AMAPT | |
| SCHEMBL22585119 | 0.77 | NR4A2 (0.46) | NR4A2GSK3BMEN1KMT2AMAPT | |
| SCHEMBL23566280 | 0.76 | NR4A2 (0.42) | NR4A2DYRK1AMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016023106-A1 | BIS-INDOLE ALKALOIDS FOR USE IN THE TREATMENT OF INFECTIONS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2016-02-18 | — | — | WO | disclosed |