SCHEMBL1753790

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1754350	0.83	TAS1R3 (0.44)	TAS1R3TAS1R1MEN1KMT2AROCK2
	SCHEMBL1754180	0.79	LMNA (0.47)	TAS1R3TAS1R1MEN1KMT2AROCK2
	SCHEMBL2330077	0.79	SMN1; SMN2 (0.47)	HPGDMEN1KMT2AROCK2ROCK1
	SCHEMBL263432	0.78	MAPK1 (0.42)	TAS1R3TAS1R1MEN1KMT2AROCK2
	SCHEMBL269225	0.78	KMT2A (0.42)	MEN1KMT2AROCK2ROCK1LMNA
	SCHEMBL263879	0.78	KMT2A (0.42)	MEN1KMT2AROCK2ROCK1LMNA
	SCHEMBL1753973	0.78	TAS1R3 (0.46)	TAS1R3TAS1R1MEN1KMT2AROCK2
	SCHEMBL3292156	0.78	TAS1R3 (0.46)	TAS1R3TAS1R1MEN1KMT2AROCK2
	SCHEMBL1753950	0.78	TAS1R3 (0.46)	TAS1R3TAS1R1MEN1KMT2AROCK2
	SCHEMBL269222	0.77	MAPK1 (0.41)	MEN1KMT2AROCK2ROCK1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.