Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 18/20 | 0.43 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13677346 | 0.86 | P2RY1 (0.44) | NPY5R | |
| SCHEMBL13016645 | 0.85 | NPY5R (0.57) | NPY5RTACR1 | |
| SCHEMBL12153109 | 0.83 | P2RY1 (0.46) | NPY5RTACR1 | |
| SCHEMBL25231257 | 0.72 | MEN1 (0.43) | NPY5RSIGMAR1TACR1 | |
| SCHEMBL17538386 | 0.72 | NOTUM (0.74) | SLC18A3SIGMAR1 | |
| SCHEMBL30733420 | 0.71 | ACLY (0.39) | NPY5RSLC18A3SIGMAR1TACR1 | |
| SCHEMBL26969777 | 0.71 | HTR6 (0.40) | NPY5RSLC18A3SIGMAR1TACR1 | |
| SCHEMBL25231173 | 0.70 | NPY5R (0.38) | NPY5RSLC18A3SIGMAR1TACR1 | |
| SCHEMBL6026997 | 0.70 | NPY5R (0.58) | NPY5RTACR1 | |
| SCHEMBL13209376 | 0.70 | SIGMAR1 (0.42) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1954287-B2 | CETP INHIBITORS | MERCK SHARP & DOHME (US) | 2016-02-24 | — | — | EP | disclosed |