SCHEMBL19958192

SCHEMBL19958192

COc1ccc(N=Nc2cc(OC)c(N=Nc3cc(OC)c(N=Nc4c(S(=O)(=O)O)cc5cc(Nc6ccccc6)ccc5c4O)cc3C)cc2C)cc1

nearest known ligand 0.75

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 10/20 0.75
PRMT1 Q99873 2/20 0.53
CARM1 Q86X55 1/20 0.53
PRMT3 O60678 1/20 0.51
EP300 Q09472 1/20 0.51
PRMT6 Q96LA8 1/20 0.51
PHLPP2 Q6ZVD8 3/20 0.50
CD40 P25942 1/20 0.47
CD40LG P29965 1/20 0.47
PTPN1 P18031 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17540350 0.98 ENPP2 (0.73) ENPP2PRMT1CARM1PRMT3EP300
SCHEMBL17540346 0.96 ENPP2 (0.79) ENPP2PRMT1CARM1PRMT3EP300
SCHEMBL17540345 0.96 ENPP2 (0.79) ENPP2PRMT1CARM1PRMT3EP300
SCHEMBL2615785 0.94 ENPP2 (0.76) ENPP2PRMT1CARM1PRMT3EP300
SCHEMBL13556981 0.94 ENPP2 (0.80) ENPP2PRMT1CARM1PRMT3EP300
SCHEMBL16417275 0.94 ENPP2 (0.80) ENPP2PRMT1CARM1PRMT3EP300
SCHEMBL19234942 0.94 ENPP2 (0.80) ENPP2PRMT1CARM1PRMT3EP300
SCHEMBL17545772 0.94 ENPP2 (0.80) ENPP2PRMT1CARM1PRMT3EP300
SCHEMBL13287624 0.94 ENPP2 (0.80) ENPP2PRMT1CARM1PRMT3EP300
SCHEMBL12758029 0.94 ENPP2 (0.71) ENPP2PRMT1CARM1PRMT3EP300

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10007142-B2 Dye-based polarizer as well as polarizing plate and liquid crystal display device using the polarizer NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2018-06-26 US disclosed
US-20180074371-A1 DYE-BASED POLARIZER AS WELL AS POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE USING THE POLARIZER POLATECHNO CO., LTD. (JP) 2018-03-15 US disclosed