SCHEMBL1754620

SCHEMBL1754620

[O-][n+]1nc(Cl)ccc1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11520424 0.75
SCHEMBL19212576 0.75
SCHEMBL11481810 0.69 ALDH1A1 (0.36)
SCHEMBL13203263 0.68
SCHEMBL9869892 0.62
SCHEMBL4901963 0.62
SCHEMBL111337 0.55
Ammonia Solution, Strong SCHEMBL25301697 0.53
SCHEMBL8801099 0.52
SCHEMBL19433235 0.50 NMT1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114671813-B Photosensitizer with fluorescence imaging and photodynamic gram-positive bacteria killing activities as well as preparation method and application thereof 内蒙古大学 2023-09-05 CN claimed
US-20080167461-A1 Process for Preparing 3,6-Dichloropyridazine-1-Oxide SANKYO AGRO COMPANY, LIMITED (JP) 2008-07-10 US claimed
EP-1862461-A1 METHOD FOR PRODUCING 3,6-DICHLOROPYRIDAZINE-1-OXIDE Sankyo Agro Company, Limited (JP) 2007-12-05 EP claimed
CN-114671813-B Photosensitizer with fluorescence imaging and photodynamic gram-positive bacteria killing activities as well as preparation method and application thereof 内蒙古大学 2023-09-05 CN disclosed
WO-2021085370-A1 AZOLE DERIVATIVE AND USE THEREOF クミアイ化学工業株式会社 2021-05-06 WO disclosed
US-9663493-B2 Pyridazine compounds, compositions and methods NORTHWESTERN UNIVERSITY (US) 2017-05-30 US disclosed
CN-102510857-B method for producing 3-substituted-oxy-4-pyridazinol derivative MITSUI CHEMICALS AGRO INC 2015-05-13 CN disclosed
US-8552182-B2 Method for producing a 3-(substituted-oxy)-4-pyridazinol derivative MITSUI CHEMICALS AGRO, INC. (JP) 2013-10-08 US disclosed
US-8367672-B2 Pyridazine compounds, compositions and methods UNIVERSITE DE STRASBOURG (FR) 2013-02-05 US disclosed
US-20120245125-A1 PYRIDAZINE COMPOUNDS, COMPOSITIONS AND METHODS UNIVERSITE LOUIS PASTEUR DE STRASBOURG (FR) 2012-09-27 US disclosed
US-20120184736-A1 METHOD FOR PRODUCING A 3-(SUBSTITUTED-OXY)-4-PYRIDAZINOL DERIVATIVE MITSUI CHEMICALS AGRO, INC (JP) 2012-07-19 US disclosed
WO-2007130383-A2 COMPOSITIONS AND TREATMENTS USING PYRIDAZINE COMPOUNDS AND SECRETASES NORTHWESTERN UNIVERSITY (US) 2007-11-15 WO disclosed
WO-2007127475-A2 PYRIDAZINES FOR DEMYELINATING DISEASES AND NEUROPATHIC PAIN NORTHWESTERN UNIVERSITY (US) 2007-11-08 WO disclosed
WO-2007127474-A2 COMPOSITIONS AND TREATMENTS USING PYRIDAZINE COMPOUNDS AND CHOLINESTERASE INHIBITORS NORTHWESTERN UNIVERSITY (US) 2007-11-08 WO disclosed
WO-2006101058-A1 METHOD FOR PRODUCING 3,6-DICHLOROPYRIDAZINE-1-OXIDE SANKYO AGRO COMPANY, LIMITED (JP) 2006-09-28 WO disclosed
US-20050037925-A1 3-phenoxy-4-pyridazinol derivatives and herbicide composition containing the same SANKYO AGRO COMPANY, LIMITED (JP) 2005-02-17 US disclosed
US-20040242886-A1 Monocyclic diazodioxide based Bcl-2 protein antagonists related applications RICERCA BIOSCIENCES, LLC. 2004-12-02 US disclosed
WO-2004099158-A1 MONOCYCLIC DIAZODIOXIDE BASED BCL-2 PROTEIN ANTAGONISTS RICERCA BIOSCIENCES, LLC. (US) 2004-11-18 WO disclosed
CN-1543455-A 3-phenoxy-4-pyridazinol derivatives and herbicidal compositions containing the same 三共农业株式会社 2004-11-03 CN disclosed
EP-1426365-A1 3-PHENOXY-4-PYRIDAZINOL DERIVATIVE AND HERBICIDE COMPOSITION CONTAINING THE SAME Sankyo Agro Company, Limited (JP) 2004-06-09 EP disclosed