Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.51 |
| ▸ | RARA | P10276 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18311384 | 0.87 | PLA2G4B (0.45) | RARBRARAHDAC1HDAC2FFAR4 | |
| SCHEMBL13038193 | 0.81 | LMNA (0.59) | RARBCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL13038243 | 0.78 | LMNA (0.64) | RARBCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL17547218 | 0.78 | RARB (0.76) | RARBPLA2G4B | |
| SCHEMBL17547129 | 0.77 | LTA4H (0.64) | RARBCYP3A4CYP2D6CYP19A1CYP2C9 | |
| SCHEMBL17547222 | 0.77 | RARB (0.62) | RARBRARACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL18625350 | 0.75 | PTGER4 (0.56) | FFAR4FFAR1PPARG | |
| SCHEMBL9253929 | 0.75 | LMNA (0.58) | RARBPLA2G4B | |
| SCHEMBL17319274 | 0.75 | RARB (0.66) | RARBCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL18736316 | 0.73 | PLA2G4B (0.61) | RARBPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2990459-B1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2017-04-26 | — | — | EP | disclosed |
| US-9594283-B2 | Polymerizable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2017-03-14 | — | — | US | disclosed |
| EP-2990459-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | Merck Patent GmbH (DE) | 2016-03-02 | — | — | EP | disclosed |