SCHEMBL9253929

SCHEMBL9253929

CCCCCOc1cccc(-c2ccc(OC(C)=O)cc2)c1

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.58
GAA P10253 1/20 0.58
MAPT P10636 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
NR1H4 Q96RI1 1/20 0.53
RARB P10826 3/20 0.51
PLA2G4B P0C869 2/20 0.51
SMPD1 P17405 3/20 0.50
PTPN11 Q06124 1/20 0.50
RXRA P19793 1/20 0.50
RXRB P28702 1/20 0.50
ACACB O00763 1/20 0.50
ACACA Q13085 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1196100 0.86 PLA2G4B (0.58) LMNANR1H4PLA2G4BSMPD1
SCHEMBL28827268 0.85 MAPT (0.51) LMNAMAPTPLA2G4BSMPD1PTPN11
SCHEMBL5737221 0.84 PLA2G4B (0.56) LMNAPLA2G4BSMPD1ACACBACACA
SCHEMBL23590265 0.83 RXRA (0.59) LMNAGAAMAPTNR1H4RARB
Ammonia Solution, Strong SCHEMBL9172111 0.83 PLA2G4B (0.59) LMNAPLA2G4BSMPD1
SCHEMBL2406965 0.82 TP53 (0.62) LMNARARBPLA2G4B
SCHEMBL4607313 0.82 LMNA (0.71) LMNAGAAMAPTTDP1RXRA
SCHEMBL8396365 0.81 TSHR (0.58) NR1H4RARBPLA2G4BSMPD1PTPN11
SCHEMBL10611011 0.81 RARB (0.74) NR1H4RARBPLA2G4BPTPN11RXRA
SCHEMBL8072237 0.81 TP53 (0.65) LMNAGAARARBPLA2G4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5385693-A Having rapid response and low phase transition temperature SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-01-31 US disclosed
EP-0357372-B1 Optically active ester derivatives, preparation process thereof, liquid crystal materials and a light switching element SUMITOMO CHEMICAL CO (JP) 1994-11-17 EP disclosed
US-5264151-A Optically active ester derivatives, preparation process thereof, liquid crystal materials and a light switching element SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-11-23 US disclosed
US-5124070-A High speed response SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-06-23 US disclosed