Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | GBA2 | Q9HCG7 | 4/20 | 0.35 |
| ▸ | GUSB | P08236 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | UGCG | Q16739 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11097330 | 1.00 | GBA1 (0.40) | GBA1SMN1; SMN2SPHK2SPHK1TYR | |
| SCHEMBL11097332 | 1.00 | GBA1 (0.40) | GBA1SMN1; SMN2SPHK2SPHK1TYR | |
| SCHEMBL8132077 | 1.00 | GBA1 (0.40) | GBA1SMN1; SMN2SPHK2SPHK1TYR | |
| SCHEMBL14387741 | 1.00 | GBA1 (0.40) | GBA1SMN1; SMN2SPHK2SPHK1TYR | |
| SCHEMBL13349959 | 1.00 | GBA1 (0.40) | GBA1SMN1; SMN2SPHK2SPHK1TYR | |
| SCHEMBL17383842 | 1.00 | GBA1 (0.40) | GBA1SMN1; SMN2SPHK2SPHK1TYR | |
| SCHEMBL3960991 | 0.95 | GBA1 (0.47) | GBA1SPHK2SPHK1GBA2ALDH1A1 | |
| SCHEMBL3960992 | 0.95 | GBA1 (0.47) | GBA1SPHK2SPHK1GBA2ALDH1A1 | |
| SCHEMBL11097755 | 0.93 | GBA1 (0.50) | GBA1SPHK2SPHK1GBA2GUSB | |
| SCHEMBL11098588 | 0.93 | GBA1 (0.50) | GBA1SPHK2SPHK1GBA2GUSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230181607-A1 | THIOSACCHARIDES FOR USE IN TREATING CORONAVIRUS INFECTION | The University of the Regents of California (US) | 2023-06-15 | — | — | US | disclosed |
| US-20180111955-A1 | THIOSACCHARIDE MUCOLYTIC AGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2018-04-26 | — | — | US | disclosed |
| US-9856283-B2 | Thiosaccharide mucolytic agents | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-01-02 | — | — | US | disclosed |
| US-20160060284-A1 | THIOSACCHARIDE MUCOLYTIC AGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2016-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180111955-A1 | THIOSACCHARIDE MUCOLYTIC AGENTS | MUC1, TREH, FUT6 | GBA1 161/4885SMN1; SMN2 4062/4885SPHK2 801/4885 |
| US-20160060284-A1 | THIOSACCHARIDE MUCOLYTIC AGENTS | MUC1, TREH, FUT6 | GBA1 161/4885SMN1; SMN2 4062/4885SPHK2 801/4885 |
| US-20230181607-A1 | THIOSACCHARIDES FOR USE IN TREATING CORONAVIRUS INFECTION | TMPRSS4, ACE, ACE2 | GBA1 361/4885SMN1; SMN2 4447/4885SPHK2 1233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.