Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | MGAM | O43451 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | SI | P14410 | 2/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.46 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.45 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28471624 | 0.88 | MEN1 (0.50) | GPR84FFAR1MEN1KMT2ASRC | |
| SCHEMBL28475935 | 0.88 | GAA (0.49) | GPR84FFAR1MEN1KMT2AMAPT | |
| SCHEMBL28471061 | 0.85 | GPR84 (0.46) | GPR84FFAR1MEN1KMT2ASRC | |
| SCHEMBL28475628 | 0.85 | NR3C1 (0.62) | GPR84FFAR1MEN1KMT2ASRC | |
| SCHEMBL28465658 | 0.81 | VDR (0.52) | GPR84FFAR1MEN1KMT2ASRC | |
| SCHEMBL28466091 | 0.80 | SRC (0.54) | GPR84MEN1KMT2ASRCMAPT | |
| SCHEMBL28465402 | 0.79 | MAPT (0.54) | GPR84FFAR1MEN1KMT2AMAPT | |
| SCHEMBL27981638 | 0.77 | GPR84 (0.77) | GPR84FFAR1MEN1KMT2ASRC | |
| SCHEMBL4331721 | 0.77 | GPR84 (0.54) | GPR84FFAR1MEN1KMT2ASRC | |
| SCHEMBL1348083 | 0.75 | CYP2D6 (0.57) | GPR84FFAR1MEN1KMT2ASRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016029310-A1 | CANNABINOID TYPE 1 RECEPTOR MODULATORS | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2016-03-03 | — | — | WO | disclosed |