Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 4/20 | 0.50 |
| ▸ | MPI | P34949 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5078088 | 1.00 | ALOX12 (0.59) | ALOX12ALDH1A1CA12CA1CA2 | |
| SCHEMBL6825334 | 1.00 | ALOX12 (0.59) | ALOX12ALDH1A1CA12CA1CA2 | |
| SCHEMBL23863733 | 0.83 | ALDH1A1 (0.52) | ALOX12ALDH1A1CA12CA1CA2 | |
| SCHEMBL533982 | 0.81 | ALOX12 (0.47) | ALOX12ALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL533983 | 0.81 | ALOX12 (0.47) | ALOX12ALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL2161592 | 0.81 | ALOX12 (0.47) | ALOX12ALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL2160910 | 0.80 | FGF23 (0.53) | ALOX12ALDH1A1KDM4EMAPTL3MBTL1 | |
| SCHEMBL406151 | 0.80 | FGF23 (0.53) | ALOX12ALDH1A1KDM4EMAPTL3MBTL1 | |
| SCHEMBL406150 | 0.80 | FGF23 (0.53) | ALOX12ALDH1A1KDM4EMAPTL3MBTL1 | |
| SCHEMBL30139909 | 0.80 | CA12 (0.62) | ALOX12ALDH1A1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210087165-A1 | PROCESS OF MAKING SOMATOSTATIN MODULATORS | Crinetics Pharmaceuticals, Inc. | 2021-03-25 | — | — | US | disclosed |
| US-10464918-B2 | Process of making somatostatin modulators | Crinetics Pharmaceuticals, Inc. (US) | 2019-11-05 | — | — | US | disclosed |
| US-20190218202-A1 | PROCESS OF MAKING SOMATOSTATIN MODULATORS | Crinetics Pharmaceuticals, Inc. | 2019-07-18 | — | — | US | disclosed |
| US-9929348-B2 | Organic semiconductor composition comprising organic semiconductor material and polymer compound | FUJIFILM CORPORATION (JP) | 2018-03-27 | — | — | US | disclosed |
| US-9929348-B2 | Organic semiconductor composition comprising organic semiconductor material and polymer compound | FUJIFILM CORPORATION (JP) | 2018-03-27 | — | — | US | disclosed |
| US-9343594-B2 | Conductive composition, conductive member and production method thereof, touch panel, and solar cell | FUJIFILM CORPORATION (JP) | 2016-05-17 | — | — | US | disclosed |
| US-9343594-B2 | Conductive composition, conductive member and production method thereof, touch panel, and solar cell | FUJIFILM CORPORATION (JP) | 2016-05-17 | — | — | US | disclosed |
| US-20160064674-A1 | ORGANIC SEMICONDUCTOR COMOSITION, ORGANIC THIN-FILM TRANSISTOR, ELECTRONIC PAPER, AND DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2016-03-03 | — | — | US | disclosed |
| US-20160064674-A1 | ORGANIC SEMICONDUCTOR COMOSITION, ORGANIC THIN-FILM TRANSISTOR, ELECTRONIC PAPER, AND DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2016-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10464918-B2 | Process of making somatostatin modulators | SSTR5, SSTR4, SSTR2 | ALOX12 1316/4885ALDH1A1 4601/4885CA12 930/4885 |
| US-20190218202-A1 | PROCESS OF MAKING SOMATOSTATIN MODULATORS | SSTR5, SSTR4, SSTR2 | ALOX12 1316/4885ALDH1A1 4601/4885CA12 930/4885 |
| US-20210087165-A1 | PROCESS OF MAKING SOMATOSTATIN MODULATORS | SSTR5, SSTR4, SSTR2 | ALOX12 1316/4885ALDH1A1 4601/4885CA12 930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.