Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Arginine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTC | P00480 | 1/20 | 0.46 |
| ▸ | DDAH1 | O94760 | 3/20 | 0.43 |
| ▸ | GSR | P00390 | 2/20 | 0.42 |
| ▸ | NOS2 | P35228 | 6/20 | 0.41 |
| ▸ | NOS3 | P29474 | 5/20 | 0.41 |
| ▸ | NOS1 | P29475 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | GRM8 | O00222 | 1/20 | 0.37 |
| ▸ | GRM6 | O15303 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Arginine SCHEMBL4203993 | 1.00 | OTC (0.46) | OTCDDAH1GSRNOS2NOS3 | |
| Arginine SCHEMBL27889814 | 1.00 | OTC (0.46) | OTCDDAH1GSRNOS2NOS3 | |
| Arginine SCHEMBL4208039 | 1.00 | OTC (0.46) | OTCDDAH1GSRNOS2NOS3 | |
| Arginine SCHEMBL28160285 | 1.00 | OTC (0.46) | OTCDDAH1GSRNOS2NOS3 | |
| Arginine SCHEMBL5965923 | 1.00 | OTC (0.46) | OTCDDAH1GSRNOS2NOS3 | |
| Arginine SCHEMBL936448 | 1.00 | OTC (0.46) | OTCDDAH1GSRNOS2NOS3 | |
| Arginine SCHEMBL26623152 | 0.96 | OTC (0.43) | OTCDDAH1GSRNOS2NOS3 | |
| Aspartic Acid SCHEMBL2028617 | 0.96 | GSR (0.45) | OTCDDAH1GSRNOS2NOS3 | |
| Arginine SCHEMBL150228 | 0.95 | OTC (0.49) | OTCDDAH1GSRNOS2NOS3 | |
| Arginine SCHEMBL27692295 | 0.95 | OTC (0.49) | OTCDDAH1GSRNOS2NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 10812 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121537486-B | Cyclic nonapeptide with anti-photoaging and anti-oxidation effects and application thereof | PROYA COSMETICS Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-122095077-A | Polyvinylpyrrolidone-based hydrogels for 3D cell culture | — | 2026-05-26 | — | — | CN | claimed |
| CN-122075745-A | Signal probe with CT and MRI imaging functions and preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122080080-A | Binuclear iridium metal conjugate, water-soluble nanoparticle, preparation method and application thereof in ultrasonic thrombolysis | — | 2026-05-26 | — | — | CN | claimed |
| CN-122060131-A | Preparation method of polypeptide composite material for biomedical additive manufacturing | 深圳百川泓沛生物科技有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122005459-A | Liposome nanoparticle for treating cardiomyopathy as well as preparation method and application thereof | 重庆市妇幼保健院(重庆市妇产科医院、重庆市遗传与生殖研究所) | 2026-05-12 | — | — | CN | claimed |
| US-12544050-B2 | Core biopsy needle | UNIV BASEL (CH) | 2026-02-10 | — | — | US | claimed |
| US-20260000700-A1 | TARGETED LINEAR CONJUGATES COMPRISING POLYETHYLENEIMINE AND POLYETHYLENE GLYCOL AND POLYPLEXES COMPRISING THE SAME | TARGIMMUNE THERAPEUTICS AG (CH) | 2026-01-01 | — | — | US | claimed |
| US-20250332298-A1 | PEPTIDE-COUPLED ALGINATE GELS COMPRISING RADIONUCLIDES | BLUE WAVE THERAPEUTICS GMBH (CH) | 2025-10-30 | — | — | US | claimed |
| US-20250333732-A1 | TREATMENT OF SOS2 RELATED DISEASES AND DISORDERS | EMPIRICO INC (US) | 2025-10-30 | — | — | US | claimed |
| WO-1995025504-A1 | EMULSIFIED DRUG DELIVERY SYSTEMS | PHARMAVENE, INC. (US) | 1995-09-28 | — | — | WO | claimed |
| WO-1995021911-A1 | HIGH PERFORMANCE CELL CULTURE BIOREACTOR AND METHOD | UNISYN TECHNOLOGIES, INC. (US) | 1995-08-17 | — | — | WO | claimed |
| EP-0664111-A2 | Biospecific emulsions | UNILEVER PLC (GB) | 1995-07-26 | — | — | EP | claimed |
| US-5416075-A | Water, oil, emulsifiers and amphipatic compound | CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) | 1995-05-16 | — | — | US | claimed |
| WO-1995012413-A1 | CELL CONTROL AND SUPPRESSION | O'BRIEN, CAROLINE, JANE (GB) | 1995-05-11 | — | — | WO | claimed |
| EP-0641222-A1 | TECHNETIUM-99m LABELED PEPTIDES FOR THROMBUS IMAGING | Diatide, Inc. (US) | 1995-03-08 | — | — | EP | claimed |
| US-5395609-A | Radioactive materials | ANTISOMA LIMITED (GB) | 1995-03-07 | — | — | US | claimed |
| WO-1993023085-A1 | TECHNETIUM-99m LABELED PEPTIDES FOR THROMBUS IMAGING | DIATECH, INC. (US) | 1993-11-25 | — | — | WO | claimed |
| EP-0419099-A1 | Proteins having anticoagulant properties | MERCK & CO. INC. (US) | 1991-03-27 | — | — | EP | claimed |
| EP-0380370-A2 | Inhibiting tumour recurrence after surgical resection | The Children's Medical Center Corporation (US) | 1990-08-01 | — | — | EP | claimed |