Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17550983 | 0.89 | TNF (0.30) | — | |
| SCHEMBL17551015 | 0.89 | TNF (0.30) | — | |
| SCHEMBL17551001 | 0.89 | — | — | |
| SCHEMBL17551002 | 0.87 | CYP2D6 (0.33) | — | |
| SCHEMBL14864775 | 0.85 | TNF (0.37) | TLR4 | |
| SCHEMBL16273574 | 0.85 | MAPK1 (0.36) | TLR4 | |
| SCHEMBL15197978 | 0.85 | MAPK1 (0.36) | TLR4 | |
| SCHEMBL17549044 | 0.84 | CYP2D6 (0.31) | — | |
| SCHEMBL17550991 | 0.83 | PAX8 (0.32) | — | |
| SCHEMBL17550999 | 0.80 | ALDH1A1 (0.34) | TLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160060365-A1 | HEPARAN SULFATE SYNTHESIS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | 2016-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160060365-A1 | HEPARAN SULFATE SYNTHESIS | HPSE, STT3B, DDOST | TLR4 2301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.