Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 3/20 | 0.37 |
| ▸ | NOS1 | P29475 | 3/20 | 0.37 |
| ▸ | NOS2 | P35228 | 3/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9321284 | 0.84 | MEN1 (0.37) | NOS3NOS1NOS2 | |
| SCHEMBL10424013 | 0.80 | NPC1 (0.39) | — | |
| SCHEMBL9320594 | 0.78 | NPC1 (0.50) | — | |
| SCHEMBL761671 | 0.77 | — | — | |
| SCHEMBL13470599 | 0.75 | — | — | |
| SCHEMBL17552003 | 0.72 | ADRA2A (0.42) | ADRA2AADRA2B | |
| SCHEMBL17551978 | 0.72 | ADRA2A (0.42) | ADRA2AADRA2B | |
| SCHEMBL28674272 | 0.70 | — | — | |
| SCHEMBL11254435 | 0.69 | MAPT (0.34) | ADRA2AADRA2B | |
| SCHEMBL28659520 | 0.69 | NOS3 (0.30) | NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1423195-B1 | HEXACOORDINATED RUTHENIUM OR OSMIUM METAL CARBENE METATHESIS CATALYSTS | CALIFORNIA INST OF TECHN (US) | 2016-03-02 | — | — | EP | disclosed |