SCHEMBL17553036

SCHEMBL17553036

C(=C/C=C/c1ccc(N(c2ccc(/C=C/C=C/C=C/c3ccccc3)cc2)c2ccc(/C=C/C=C/c3ccccc3)cc2)cc1)\C=C\c1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAOB P27338 2/20 0.64
▸ APP P05067 6/20 0.56
▸ RELA Q04206 1/20 0.54
▸ ALDH1A1 P00352 2/20 0.48
▸ MAPK1 P28482 2/20 0.48
▸ TRPA1 O75762 1/20 0.48
▸ LMNA P02545 1/20 0.48
▸ ALOX5 P09917 1/20 0.48
▸ MAPT P10636 2/20 0.43
▸ KDM4E B2RXH2 1/20 0.43
▸ CYP1A2 P05177 1/20 0.43
▸ CYP3A4 P08684 1/20 0.43
▸ CYP2D6 P10635 1/20 0.43
▸ CYP2C9 P11712 1/20 0.43
▸ CYP2C19 P33261 1/20 0.43
▸ TDP1 Q9NUW8 1/20 0.43
▸ L3MBTL1 Q9Y468 1/20 0.43
▸ NFE2L2 Q16236 1/20 0.43
▸ CYP19A1 P11511 1/20 0.43
▸ MAOA P21397 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17553042 1.00 MAOB (0.64) MAOBAPPRELAALDH1A1MAPK1
SCHEMBL17553034 0.98 MAOB (0.61) MAOBAPPRELAALDH1A1MAPK1
SCHEMBL17553032 0.98 MAOB (0.61) MAOBAPPRELAALDH1A1MAPK1
SCHEMBL17367869 0.98 MAOB (0.67) MAOBAPPRELAALDH1A1MAPK1
SCHEMBL18418092 0.95 MAOB (0.64) MAOBAPPRELAALDH1A1MAPK1
SCHEMBL18418095 0.95 MAOB (0.64) MAOBAPPRELAALDH1A1MAPK1
SCHEMBL17553038 0.95 MAOB (0.64) MAOBAPPRELAALDH1A1MAPK1
SCHEMBL15900026 0.95 MAOB (0.64) MAOBAPPRELAALDH1A1MAPK1
SCHEMBL18418094 0.95 MAOB (0.64) MAOBAPPRELAALDH1A1MAPK1
SCHEMBL2622609 0.95 MAOB (0.64) MAOBAPPRELAALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9933712-B2 Multi-layer electrophotographic photosensitive member, process cartridge, and image forming apparatus KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2018-04-03 — — US disclosed
US-9933712-B2 Multi-layer electrophotographic photosensitive member, process cartridge, and image forming apparatus KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2018-04-03 — — US disclosed
US-9690217-B2 Triarylamine derivative, electrophotographic photosensitive member, and image forming apparatus Kyocera Document Solutions, Inc. (JP) 2017-06-27 — — US disclosed
US-9690217-B2 Triarylamine derivative, electrophotographic photosensitive member, and image forming apparatus Kyocera Document Solutions, Inc. (JP) 2017-06-27 — — US disclosed
US-20170060006-A1 MULTI-LAYER ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2017-03-02 — — US disclosed
US-20170060006-A1 MULTI-LAYER ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2017-03-02 — — US disclosed
EP-3136175-A1 MULTI-LAYER ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, METHOD FOR PRODUCING THE SAME, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS Kyocera Document Solutions Inc. (JP) 2017-03-01 — — EP disclosed
US-20160062253-A1 TRIARYLAMINE DERIVATIVE, ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMEBER, AND IMAGE FORMING APPARATUS KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2016-03-03 — — US disclosed
US-20160062253-A1 TRIARYLAMINE DERIVATIVE, ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMEBER, AND IMAGE FORMING APPARATUS KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2016-03-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160062253-A1 TRIARYLAMINE DERIVATIVE, ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMEBER, AND IMAGE FORMING APPARATUS AADAT, PNMT, KMO MAOB 227/4885APP 1412/4885RELA 3692/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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