Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.49 |
| ▸ | MMP3 | P08254 | 2/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | REN | P00797 | 2/20 | 0.42 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.42 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | CCKBR | P32239 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17553516 | 0.96 | MMP1 (0.46) | MMP1MMP3MMP9PAX8TDP1 | |
| SCHEMBL17553452 | 0.95 | MMP1 (0.46) | MMP1MMP3MMP9PAX8TDP1 | |
| SCHEMBL17553611 | 0.92 | MMP1 (0.43) | MMP1MMP3MMP9PAX8TDP1 | |
| SCHEMBL17553672 | 0.85 | MMP1 (0.42) | MMP1MMP3MMP9PAX8TDP1 | |
| SCHEMBL17553572 | 0.85 | MMP1 (0.43) | MMP1MMP3MMP9PAX8TDP1 | |
| SCHEMBL17553673 | 0.81 | MMP1 (0.45) | MMP1MMP3MMP9PAX8TDP1 | |
| SCHEMBL17553513 | 0.80 | MMP1 (0.46) | MMP1MMP3MMP9PAX8TDP1 | |
| SCHEMBL17553447 | 0.79 | MMP1 (0.59) | MMP1MMP3MMP9PAX8TDP1 | |
| SCHEMBL17553449 | 0.78 | GHSR (0.53) | — | |
| SCHEMBL16908988 | 0.75 | ACE (0.59) | MMP1MMP3MMP9PAX8TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016029324-A1 | AZASULFURYLPEPTIDE-BASED CD36 MODULATORS AND USES THEREOF | RSEM, LIMITED PARTNERSHIP (CA) | 2016-03-03 | — | — | WO | disclosed |