SCHEMBL17553572

CNC(=O)[C@H](CCCCNC(=O)OC(C)(C)C)NC(=O)[C@@H](Cc1ccccc1)NS(=O)(=O)N(Cc1ccccc1)NC(=O)[C@H](C)NC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.54

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	MMP1	P03956	1/20	0.43

▸	MMP3	P08254	1/20	0.43

▸	MMP9	P14780	1/20	0.43

▸	TLR2	O60603	1/20	0.41

▸	TLR1	Q15399	1/20	0.41

▸	PAX8	Q06710	1/20	0.40

▸	TDP1	Q9NUW8	1/20	0.40

▸	REN	P00797	2/20	0.39

▸	KMT2A	Q03164	2/20	0.38

▸	MDM2	Q00987	1/20	0.38

▸	PTPN1	P18031	3/20	0.38

▸	MEN1	O00255	1/20	0.38

▸	GRB2	P62993	1/20	0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL17553512	0.86	MMP1 (0.40)	MMP1MMP3MMP9TLR2TLR1
SCHEMBL17553515	0.85	MMP1 (0.49)	MMP1MMP3MMP9PAX8TDP1
SCHEMBL17553672	0.84	MMP1 (0.42)	MMP1MMP3MMP9PAX8TDP1
SCHEMBL30193482	0.82	MDM2 (0.48)	TLR2TLR1PAX8TDP1REN
SCHEMBL16870092	0.82	MDM2 (0.48)	TLR2TLR1PAX8TDP1REN
SCHEMBL23922657	0.82	MDM2 (0.48)	TLR2TLR1PAX8TDP1REN
SCHEMBL30193352	0.82	MDM2 (0.48)	TLR2TLR1PAX8TDP1REN
SCHEMBL17553602	0.82	CASP3 (0.47)	PTPN1
SCHEMBL17553516	0.81	MMP1 (0.46)	MMP1MMP3MMP9PAX8TDP1
SCHEMBL29431191	0.81	MDM2 (0.51)	TLR2TLR1PAX8TDP1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2016029324-A1	AZASULFURYLPEPTIDE-BASED CD36 MODULATORS AND USES THEREOF	RSEM, LIMITED PARTNERSHIP (CA)	2016-03-03	—	—	WO	disclosed