SCHEMBL17554253

SCHEMBL17554253

CCCCCCCCCCCCCCC(CO)N=[N+]=[N-]

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.48
SGPL1 O95470 4/20 0.43
CYP2D6 P10635 2/20 0.41
SPHK1 Q9NYA1 1/20 0.41
GMNN O75496 1/20 0.41
POLB P06746 1/20 0.41
THPO P40225 1/20 0.41
MTOR P42345 1/20 0.41
BLM P54132 1/20 0.41
KDM4E B2RXH2 1/20 0.41
TP53 P04637 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
MAPT P10636 1/20 0.41
CETP P11597 1/20 0.41
HTT P42858 1/20 0.41
UBE2N P61088 1/20 0.41
FDPS P14324 4/20 0.39
LAP3 P28838 1/20 0.37
CA2 P00918 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17554258 1.00 LMNA (0.48) LMNASGPL1CYP2D6SPHK1GMNN
SCHEMBL17554254 1.00 LMNA (0.48) LMNASGPL1CYP2D6SPHK1GMNN
SCHEMBL14848265 0.87 SGPL1 (0.44) LMNASGPL1FDPSLAP3CA2
SCHEMBL13637149 0.87 SGPL1 (0.44) LMNASGPL1FDPSLAP3CA2
SCHEMBL28664154 0.87 SGPL1 (0.44) LMNASGPL1FDPSLAP3CA2
SCHEMBL13784736 0.86 SGPL1 (0.42) LMNASGPL1CYP2D6SPHK1GMNN
SCHEMBL16358397 0.85 SGPL1 (0.42) LMNASGPL1FDPSLAP3CA2
SCHEMBL15368891 0.83 SGPL1 (0.41) LMNASGPL1FDPSLAP3CA2
SCHEMBL13827706 0.83 SGPL1 (0.41) LMNASGPL1FDPSLAP3CA2
SCHEMBL27472493 0.83 SGPL1 (0.41) LMNASGPL1FDPSLAP3CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2993182-B1 IMMUNITY INDUCER FOR SACCHARIDE ANTIGENS AIST (JP) 2020-10-14 EP disclosed
US-10307471-B2 Immunity inducer for saccharide antigens NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2019-06-04 US disclosed
US-20160074522-A1 IMMUNITY INDUCER FOR SACCHARIDE ANTIGENS NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2016-03-17 US disclosed
EP-2993182-A1 IMMUNITY INDUCER FOR SACCHARIDE ANTIGENS National Institute of Advanced Industrial Science and Technology (JP) 2016-03-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10307471-B2 Immunity inducer for saccharide antigens CD14, CD4, CD69 LMNA 4770/4885SGPL1 573/4885CYP2D6 4105/4885
US-20160074522-A1 IMMUNITY INDUCER FOR SACCHARIDE ANTIGENS CD14, CD4, CD69 LMNA 4755/4885SGPL1 577/4885CYP2D6 4164/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.