Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 2/20 | 0.47 |
| ▸ | CASP7 | P55210 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9424812 | 0.83 | PARP1 (0.46) | CHRM1TDP1PARP1PARP2TSHR | |
| SCHEMBL3302983 | 0.81 | KDM4E (0.49) | KDM4EHSD17B10ALDH1A1GLAHPGD | |
| SCHEMBL28158393 | 0.81 | KDM4E (0.53) | KDM4EHSD17B10ALDH1A1GLAHPGD | |
| SCHEMBL2330449 | 0.76 | PARP1 (0.50) | KDM4ECHRM1PARP1PARP2TSHR | |
| SCHEMBL3458914 | 0.74 | ALDH1A1 (0.65) | KDM4EHSD17B10ALDH1A1GLAHPGD | |
| SCHEMBL4149713 | 0.74 | KDM4E (0.51) | KDM4EHSD17B10ALDH1A1GLAHPGD | |
| SCHEMBL10697117 | 0.74 | MAPT (0.42) | SMN1; SMN2PARP1PARP2MAPTHTT | |
| SCHEMBL1218835 | 0.73 | TDP1 (0.67) | KDM4ETDP1PARP1KMT2AFFAR1 | |
| SCHEMBL30307853 | 0.73 | TDP1 (0.67) | KDM4ETDP1PARP1KMT2AFFAR1 | |
| SCHEMBL9095253 | 0.73 | KDM4E (0.58) | KDM4EALDH1A1GLAHPGDCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2993476-A1 | AUTOPHAGY AND PHOSPHOLIPIDOSIS PATHWAY ASSAYS | Enzo Life Sciences, Inc. (US) | 2016-03-09 | — | — | EP | disclosed |