SCHEMBL3302983

SCHEMBL3302983

Nc1c2ccccc2nc2cccc(CCC(O)O)c12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.49
ALDH1A1 P00352 7/20 0.49
HPGD P15428 6/20 0.49
HSD17B10 Q99714 5/20 0.49
GLA P06280 4/20 0.49
CASP1 P29466 3/20 0.49
CASP7 P55210 3/20 0.49
SMN1; SMN2 Q16637 3/20 0.49
ACHE P22303 3/20 0.49
CHRM2 P08172 2/20 0.49
ADRA2A P08913 2/20 0.49
ADORA3 P0DMS8 2/20 0.49
CHRM1 P11229 2/20 0.49
SLC6A2 P23975 2/20 0.49
OPRM1 P35372 2/20 0.49
KCNH2 Q12809 2/20 0.49
NQO2 P16083 1/20 0.49
MAOA P21397 1/20 0.49
DRD1 P21728 1/20 0.49
ADRA1A P35348 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28158393 0.82 KDM4E (0.53) KDM4EALDH1A1HPGDHSD17B10GLA
SCHEMBL17554288 0.81 KDM4E (0.47) KDM4EALDH1A1HPGDHSD17B10GLA
SCHEMBL3458914 0.76 ALDH1A1 (0.65) KDM4EALDH1A1HPGDHSD17B10GLA
Hydrochloric Acid SCHEMBL3242596 0.74 RAB9A (0.67) KDM4EALDH1A1HPGDHSD17B10GLA
SCHEMBL17066273 0.73 CYP1A2 (0.64) KDM4EALDH1A1HPGDHSD17B10GLA
SCHEMBL27438758 0.71 KMT2A (0.39) KDM4EALDH1A1HPGDHSD17B10GLA
SCHEMBL11282568 0.71 KDM4E (0.46) KDM4EALDH1A1HPGDHSD17B10GLA
SCHEMBL9849700 0.71 CYP19A1 (0.51) ALDH1A1HSD17B10SMN1; SMN2GAAPOLB
SCHEMBL11052646 0.69 ALDH1A1 (0.61) KDM4EALDH1A1HPGDHSD17B10GLA
SCHEMBL11054708 0.69 ACHE (0.61) KDM4EALDH1A1HPGDHSD17B10GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2993476-B1 AUTOPHAGY AND PHOSPHOLIPIDOSIS PATHWAY ASSAYS ENZO LIFE SCIENCES INC (US) 2018-12-26 EP claimed
EP-2993476-A1 AUTOPHAGY AND PHOSPHOLIPIDOSIS PATHWAY ASSAYS Enzo Life Sciences, Inc. (US) 2016-03-09 EP claimed
EP-2499495-A1 AUTOPHAGY AND PHOSPHOLIPIDOSIS PATHWAY ASSAYS Enzo Life Sciences, Inc. (US) 2012-09-19 EP claimed
WO-2011031330-A1 AUTOPHAGY AND PHOSPHOLIPIDOSIS PATHWAY ASSAYS ENZO LIFE SCIENCES, INC. (US) 2011-03-17 WO claimed
US-20100093004-A1 Autophagy and phospholipidosis pathway assays ENZO LIFE SCIENCES, INC. 2010-04-15 US claimed
EP-2993476-B1 AUTOPHAGY AND PHOSPHOLIPIDOSIS PATHWAY ASSAYS ENZO LIFE SCIENCES INC (US) 2018-12-26 EP disclosed
EP-3001199-B1 AUTOPHAGY AND PHOSPHOLIPIDOSIS PATHWAY ASSAYS ENZO LIFE SCIENCES INC (US) 2018-03-21 EP disclosed
EP-3001199-A1 AUTOPHAGY AND PHOSPHOLIPIDOSIS PATHWAY ASSAYS Enzo Life Sciences, Inc. (US) 2016-03-30 EP disclosed
EP-2499495-B1 Autophagy and phospholipidosis pathway assays ENZO LIFE SCIENCES INC (US) 2016-03-30 EP disclosed
EP-2993476-A1 AUTOPHAGY AND PHOSPHOLIPIDOSIS PATHWAY ASSAYS Enzo Life Sciences, Inc. (US) 2016-03-09 EP disclosed
EP-2993477-A1 AUTOPHAGY AND PHOSPHOLIPIDOSIS PATHWAY ASSAYS Enzo Life Sciences, Inc. (US) 2016-03-09 EP disclosed
US-9250249-B2 Autophagy and phospholipidosis pathway assays ENZO BIOCHEM, INC. (US) 2016-02-02 US disclosed
EP-2499495-A1 AUTOPHAGY AND PHOSPHOLIPIDOSIS PATHWAY ASSAYS Enzo Life Sciences, Inc. (US) 2012-09-19 EP disclosed
WO-2011031330-A1 AUTOPHAGY AND PHOSPHOLIPIDOSIS PATHWAY ASSAYS ENZO LIFE SCIENCES, INC. (US) 2011-03-17 WO disclosed
US-20100093004-A1 Autophagy and phospholipidosis pathway assays ENZO LIFE SCIENCES, INC. 2010-04-15 US disclosed