SCHEMBL1755481

SCHEMBL1755481

CCCCc1cc(Sc2cc(C)c(O)c(C(C)CC)c2)cc(C)c1O

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.32
TYR P14679 2/20 0.32
ALOX5 P09917 4/20 0.31
TSHR P16473 1/20 0.31
PTGS2 P35354 3/20 0.31
NPC1 O15118 1/20 0.30
HPGD P15428 1/20 0.30
MAPK1 P28482 1/20 0.30
HTT P42858 1/20 0.30
RAB9A P51151 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
RORC P51449 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4584092 0.86 TYR (0.41) MAOATYRALOX5TSHRPTGS2
SCHEMBL9745295 0.80 ALOX5 (0.46) TYRALOX5TSHRPTGS2HTT
SCHEMBL10894181 0.80 ALOX5 (0.46) TYRALOX5TSHRPTGS2HTT
SCHEMBL10894467 0.80 ALOX5 (0.46) TYRALOX5TSHRPTGS2HTT
SCHEMBL14263568 0.77 HPN (0.38) TYRALOX5TSHRPTGS2RORC
SCHEMBL10933792 0.76 TYR (0.46) MAOATYRALOX5TSHRPTGS2
SCHEMBL3129487 0.76 TSHR (0.45) TSHRHPGDRORC
SCHEMBL12457769 0.76 HTT (0.38) MAOATYRALOX5TSHRPTGS2
SCHEMBL13929512 0.76 TYR (0.38) MAOATYRALOX5TSHRPTGS2
SCHEMBL11801294 0.74 TSHR (0.38) TSHRHPGDRORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8217105-B2 Stabilized medium and high voltage insulation composition BASF SE (DE) 2012-07-10 US disclosed
EP-2074167-B1 STABILIZED MEDIUM AND HIGH VOLTAGE INSULATION COMPOSITION BASF SE (DE) 2012-04-18 EP disclosed
US-20100036031-A1 STABILIZED MEDIUM AND HIGH VOLTAGE INSULATION COMPOSITION CIBA CORPORATION 2010-02-11 US disclosed
WO-2008046751-A2 STABILIZED MEDIUM AND HIGH VOLTAGE INSULATION COMPOSITION CIBA HOLDING INC. (CH) 2008-04-24 WO disclosed