SCHEMBL4584092

SCHEMBL4584092

CCCCc1cc(Sc2cc(C)c(O)c(CCCC)c2)cc(C)c1O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 3/20 0.41
ALOX5 P09917 5/20 0.39
HTT P42858 3/20 0.39
NPC1 O15118 1/20 0.39
HPGD P15428 1/20 0.39
MAPK1 P28482 1/20 0.39
RAB9A P51151 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
MAOA P21397 1/20 0.39
PTGS2 P35354 3/20 0.38
ESR1 P03372 3/20 0.36
EGFR P00533 1/20 0.35
MAPT P10636 2/20 0.35
MEN1 O00255 1/20 0.35
TP53 P04637 1/20 0.35
CYP3A4 P08684 1/20 0.35
ALOX15 P16050 1/20 0.35
TSHR P16473 1/20 0.35
KMT2A Q03164 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10894467 0.93 ALOX5 (0.46) TYRALOX5HTTPTGS2ESR1
SCHEMBL10894181 0.93 ALOX5 (0.46) TYRALOX5HTTPTGS2ESR1
SCHEMBL9745295 0.93 ALOX5 (0.46) TYRALOX5HTTPTGS2ESR1
SCHEMBL10933792 0.89 TYR (0.46) TYRALOX5HTTNPC1HPGD
SCHEMBL1755481 0.86 MAOA (0.32) TYRALOX5HTTNPC1HPGD
SCHEMBL12457005 0.85 TYR (0.40) TYRALOX5HTTNPC1HPGD
SCHEMBL9744224 0.81 PTGS2 (0.51) TYRALOX5HTTPTGS2ESR1
SCHEMBL9297983 0.81 MAPT (0.40) ALOX5HTTNPC1HPGDMAOA
SCHEMBL10977917 0.80 NR1H2 (0.44) TYRALOX5HTTHPGDMAOA
SCHEMBL13851418 0.79 ALOX5 (0.54) TYRALOX5HTTNPC1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0965999-B1 A crosslinkable polyolefin composition UNION CARBIDE CHEM PLASTIC (US) 2005-10-26 EP claimed
US-6228917-B1 CONTAINING SCORCH INHIBITOR, CURE BOOSTER AND ORGANIC PEROXIDE UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION 2001-05-08 US claimed
EP-0965999-A1 A crosslinkable polyolefin composition UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1999-12-22 EP claimed
EP-0132717-B1 HEAT-SENSITIVE RECORD MATERIAL KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1987-04-22 EP claimed
US-20210371559-A1 ETHYLENE-ALPHA-OLEFIN-NONCONJUGATED POLYENE COPOLYMER RUBBER AND RUBBER COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-12-02 US disclosed
EP-3877431-A1 ETHYLENE-ALPHA-OLEFIN-NONCONJUGATED POLYENE COPOLYMER RUBBER AND RUBBER COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-09-15 EP disclosed
US-20210255544-A1 RESIST COMPOSITION SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-08-19 US disclosed
US-10435494-B2 Ethylene/α-olefin/non-conjugated polyene copolymer, and production process and use thereof MITSUI CHEMICALS, INC. (JP) 2019-10-08 US disclosed
CN-109996819-A METHOD FOR PRODUCING ACRYLIC RUBBER 日本瑞翁株式会社 2019-07-09 CN disclosed
US-10131726-B2 Ethylene/α-olefin/non-conjugated polyene copolymer, and production process and use thereof MITSUI CHEMICALS, INC. (JP) 2018-11-20 US disclosed
US-20180319917-A1 ETHYLENE/ALPHA-OLEFIN/NON-CONJUGATED POLYENE COPOLYMER, AND PRODUCTION PROCESS AND USE THEREOF MITSUI CHEMICALS, INC. (JP) 2018-11-08 US disclosed
EP-3336143-A1 ETHYLENE-ALPHA-OLEFIN COPOLYMER RUBBER, RUBBER COMPOSITION, AND METHOD FOR PRODUCING ETHYLENE-ALPHA-OLEFIN COPOLYMER RUBBER Sumitomo Chemical Company, Limited (JP) 2018-06-20 EP disclosed
EP-0842957-A1 ETHYLENIC RANDOM COPOLYMER, PROCESS FOR PREPARING THE SAME, AND RUBBER COMPOSITION Mitsui Chemicals, Inc. (JP) 1998-05-20 EP disclosed
US-5194572-A Phosphite stabilizers, polyesters, ester interchange AMOCO CORPORATION (US) 1993-03-16 US disclosed
US-5138025-A Adding low molecular weight monohydric alcohols and organic phosphites; polyesters AMOCO CORPORATION (US) 1992-08-11 US disclosed
EP-0161794-B1 PREPARING CLINDAMYCIN AND ANALOGUES THEREOF THE UPJOHN COMPANY (US) 1990-06-27 EP disclosed
US-4833181-A METALLIC SOAP, AMINE ANTIOXIDANT TONEN SEKIYUKAGAKU KABUSHIKI KAISHA (JP) 1989-05-23 US disclosed
US-4568741-A Synthesis of 7-halo-7-deoxylincomycins THE UPJOHN COMPANY (US) 1986-02-04 US disclosed
EP-0161794-A2 Preparing clindamycin and analogues thereof THE UPJOHN COMPANY (US) 1985-11-21 EP disclosed
US-3987033-A ENHANCING ADHESION OF POLYESTERS TO ELASTOMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-10-19 US disclosed