SCHEMBL3129487

SCHEMBL3129487

CCC(C)c1cc(Sc2cc(C(C)CC)c(O)c(C(C)CC)c2)cc(C(C)CC)c1O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.45
RORC P51449 1/20 0.42
HPGD P15428 2/20 0.39
USP2 O75604 1/20 0.39
ALDH1A1 P00352 1/20 0.39
GAA P10253 1/20 0.39
PKM P14618 1/20 0.39
ALOX15 P16050 1/20 0.39
HSD17B10 Q99714 1/20 0.39
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
GABRA1 P14867 4/20 0.34
GABRB1 P18505 4/20 0.34
GABRB2 P47870 2/20 0.34
HDAC4 P56524 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
GSR P00390 1/20 0.33
FAAH O00519 1/20 0.32
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10893299 0.94 CA1 (0.47) TSHRRORCHPGDUSP2ALDH1A1
SCHEMBL11803509 0.84 TSHR (0.37) TSHRRORCALDH1A1GAAPKM
SCHEMBL11795634 0.84 TSHR (0.37) TSHRRORCHPGDUSP2ALDH1A1
SCHEMBL9418462 0.84 CA1 (0.34) TSHRHPGDUSP2ALDH1A1GAA
SCHEMBL203191 0.81 RORC (0.45) TSHRRORCHPGDUSP2ALDH1A1
SCHEMBL10946690 0.80 CA1 (0.58) TSHRRORCHPGDUSP2ALDH1A1
SCHEMBL11207202 0.80 RORC (0.56) TSHRRORCHPGDUSP2ALDH1A1
SCHEMBL1836944 0.78 TSHR (0.48) TSHRRORCHPGDUSP2ALDH1A1
SCHEMBL6943323 0.78 TSHR (0.48) TSHRRORCHPGDUSP2ALDH1A1
SCHEMBL199923 0.78 MAOA (0.41) TSHRRORCHPGDUSP2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4626259-A ADDITIVE OF ORGANIC NITRATE IGNITION ACCELERATOR AND 4,4'-THIOBISPHENOLS; REDUCED COKING OF INJECTOR NOZZLES ETHYL CORPORATION (US) 1986-12-02 US claimed
WO-2015105704-A1 ALKYLATED NAPHTHALENE BASED LUBRICANT FOR AMMONIA REFRIGERATION JAX INC. (US) 2015-07-16 WO disclosed
US-20150197706-A1 AMMONIA REFRIGERATION COMPRESSOR AND TRANSFER PUMP LUBRICATING OIL BASED ON ALKYLATED NAPHTHALENES JAX INC. (US) 2015-07-16 US disclosed
US-8357641-B2 Food grade compressor/vacuum pump cleaner JAX INC. (US) 2013-01-22 US disclosed
US-8183188-B2 Food grade Compressor/Vacuum pump oil JAX INC. (US) 2012-05-22 US disclosed
US-20100093571-A1 Food Grade Compressor/Vacuum Pump Oil JAX INC. 2010-04-15 US disclosed
US-20100093570-A1 Food Grade Compressor/Vacuum Pump Cleaner JAX INC. 2010-04-15 US disclosed
US-20100093572-A1 Food Grade Rotary Screw Compressor Lubricant JAX INC. 2010-04-15 US disclosed
EP-1939272-A1 Food grade lubricant compositions Afton Chemical Corporation (US) 2008-07-02 EP disclosed
US-20080125338-A1 FOOD GRADE LUBRICANT COMPOSITIONS AFTON CHEMICAL CORPORATION 2008-05-29 US disclosed
US-5102567-A Odorless, colorless and tasteless hydrocarabon oil and an antioxidant additive; for use in food processing AMOCO CORPORATION (US) 1992-04-07 US disclosed
US-4626259-A ADDITIVE OF ORGANIC NITRATE IGNITION ACCELERATOR AND 4,4'-THIOBISPHENOLS; REDUCED COKING OF INJECTOR NOZZLES ETHYL CORPORATION (US) 1986-12-02 US disclosed
US-4088587-A ANTIOXIDANT AND PHOSPHORUS-CONTAINING COMPOSITION CHEVRON RESEARCH COMPANY (US) 1978-05-09 US disclosed
US-4032462-A AN ANTIOXIDANT AND AN ORGANO-ANTIMONY COMPOUND CHEVRON RESEARCH COMPANY (US) 1977-06-28 US disclosed
US-3992307-A BIS-PHOSPHORAMIDE CHEVRON RESEARCH COMPANY (US) 1976-11-16 US disclosed
US-3958624-A Heat transfer fluids CHEVRON RESEARCH COMPANY (US) 1976-05-25 US disclosed