SCHEMBL175579

SCHEMBL175579

CC(=O)Nc1ccc(C=Cc2ccc(N3C(=O)C=CC3=O)cc2S(=O)(=O)O)c(S(=O)(=O)O)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 2/20 0.67
HSP90AA1 P07900 2/20 0.53
TLR9 Q9NR96 1/20 0.53
RAD51 Q06609 3/20 0.45
ALDH1A1 P00352 4/20 0.43
MEN1 O00255 3/20 0.43
MAPT P10636 3/20 0.43
KMT2A Q03164 3/20 0.43
HPGD P15428 2/20 0.43
G6PD P11413 1/20 0.43
PKM P14618 1/20 0.43
CCR6 P51684 1/20 0.43
MCL1 Q07820 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
ATAD2 Q6PL18 1/20 0.41
CECR2 Q9BXF3 1/20 0.41
APEX1 P27695 1/20 0.41
POLB P06746 1/20 0.40
SCN2A Q99250 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL175578 1.00 ENPP2 (0.67) ENPP2HSP90AA1TLR9RAD51ALDH1A1
SCHEMBL31508347 1.00 ENPP2 (0.67) ENPP2HSP90AA1TLR9RAD51ALDH1A1
SCHEMBL29950285 0.89 RAD51 (0.58) ENPP2HSP90AA1TLR9RAD51ALDH1A1
SCHEMBL9321055 0.85 ENPP2 (0.91) ENPP2RAD51ALDH1A1MEN1MAPT
SCHEMBL14358432 0.85 ENPP2 (0.91) ENPP2RAD51ALDH1A1MEN1MAPT
SCHEMBL7712332 0.83 ENPP2 (0.46) ENPP2HSP90AA1TLR9ALDH1A1MEN1
SCHEMBL7712325 0.83 ENPP2 (0.46) ENPP2HSP90AA1TLR9ALDH1A1MEN1
SCHEMBL14620709 0.80 ENPP2 (0.78) ENPP2RAD51ALDH1A1MEN1MAPT
SCHEMBL11421159 0.80 ENPP2 (0.78) ENPP2RAD51ALDH1A1MEN1MAPT
SCHEMBL29673349 0.79 HSP90AA1 (0.43) ENPP2HSP90AA1ALDH1A1PKMNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12415930-B2 Conductive polymer composition, substrate, and method for producing substrate SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-09-16 US disclosed
US-12415931-B2 Conductive polymer composition, substrate, and method for producing substrate SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-09-16 US disclosed
US-12398288-B2 Conductive polymer composition, substrate, and method for producing substrate SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-08-26 US disclosed
WO-2025047827-A1 PROTEIN FOLDING AGENT, COMPOUND, PROTEIN FOLDING METHOD, PHARMACEUTICAL COMPOSITION, AND AGENT FOR SUPPRESSING CYTOTOXICITY BY TRANSITION METAL 国立大学法人東京農工大学 2025-03-06 WO disclosed
EP-4067437-B1 CONDUCTIVE POLYMER COMPOSITION, SUBSTRATE, AND METHOD FOR PRODUCING SUBSTRATE SHINETSU CHEMICAL CO (JP) 2024-08-21 EP disclosed
US-20240207207-A1 METHODS FOR MITIGATING AND PREVENTING PROTEOSTASIS-BASED INJURIES SAN DIEGO STATE UNIV SDSU FOUNDATION DBA SAN DIEGO STATE UNIV RESEARCH FOUNDATION (US) 2024-06-27 US disclosed
EP-4361179-A1 FUSION PROTEIN, FUSION PROTEIN PRODUCTION METHOD, ELECTRODE, REDOX DEVICE, REDOX METHOD, METHOD FOR CUTTING DISULFIDE BONDS, AND METHOD FOR INACTIVATING ALLERGEN Panasonic Intellectual Property Management Co., Ltd. (JP) 2024-05-01 EP disclosed
US-20240117325-A1 FUSION PROTEIN, FUSION PROTEIN PRODUCTION METHOD, ELECTRODE, REDOX DEVICE, REDOX METHOD, DISULFIDE BOND CLEAVAGE METHOD, AND ALLERGEN INACTIVATION METHOD PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO, LTD. (JP) 2024-04-11 US disclosed
US-11801262-B2 Antibiotic compositions THIOREDOXIN SYSTEMS AB (SE) 2023-10-31 US disclosed
US-20230159766-A1 CONDUCTIVE POLYMER COMPOSITION, SUBSTRATE, AND METHOD FOR PRODUCING SUBSTRATE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-05-25 US disclosed
US-7410788-B2 Compositions and methods for production of disulfide bond containing proteins in host cells PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2008-08-12 US disclosed
EP-1947655-A1 TRANSPARENT CONDUCTIVE SHEET FOR TOUCH PANEL, METHOD FOR MANUFACTURING SAME AND TOUCH PANEL SHIN-ETSU POLYMER CO., LTD. (JP) 2008-07-23 EP disclosed
WO-2007127735-A2 PROKARYOTIC HOST CELLS FOR EXPRESSING PROTEINS RICH IN DISULFIDE BONDS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2007-11-08 WO disclosed
US-20070254334-A1 Prokaryotic host cells for expressing proteins rich in disulfide bonds PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2007-11-01 US disclosed
EP-1718323-A2 BINDING PEPTIDOMIMETICS AND USES OF THE SAME The Trustees of The University of Pennsylvania (US) 2006-11-08 EP disclosed
US-20060047030-A1 Conductive composition and conductive cross-linked product, capacitor and production method thereof, and antistatic coating material, antistatic coating, antistatic film, optical filter, and optical information recording medium SHIN-ETSU POLYMER CO., LTD 2006-03-02 US disclosed
US-20060030022-A1 Compositions and methods for production of disulfide bond containing proteins in host cells NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2006-02-09 US disclosed
WO-2005081898-A2 BINDING PEPTIDOMIMETICS AND USES OF THE SAME THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2005-09-09 WO disclosed
US-6872563-B1 Compositions and methods for production of disulfide bond containing proteins in host cells PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2005-03-29 US disclosed
WO-2004056987-A1 MODULATION OF THE THIOREDOXIN PATHWAY RIJKSUNIVERSITEIT GRONINGEN (NL) 2004-07-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240207207-A1 METHODS FOR MITIGATING AND PREVENTING PROTEOSTASIS-BASED INJURIES ATF4, XBP1, HSPA5 ENPP2 2497/4885HSP90AA1 37/4885TLR9 3877/4885
US-11801262-B2 Antibiotic compositions MRPL21, RPS5, MRPS35 ENPP2 4635/4885HSP90AA1 126/4885TLR9 1711/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.