Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.67 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.53 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.53 |
| ▸ | RAD51 | Q06609 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | G6PD | P11413 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.41 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL175578 | 1.00 | ENPP2 (0.67) | ENPP2HSP90AA1TLR9RAD51ALDH1A1 | |
| SCHEMBL175579 | 1.00 | ENPP2 (0.67) | ENPP2HSP90AA1TLR9RAD51ALDH1A1 | |
| SCHEMBL29950285 | 0.89 | RAD51 (0.58) | ENPP2HSP90AA1TLR9RAD51ALDH1A1 | |
| SCHEMBL9321055 | 0.85 | ENPP2 (0.91) | ENPP2RAD51ALDH1A1MEN1MAPT | |
| SCHEMBL14358432 | 0.85 | ENPP2 (0.91) | ENPP2RAD51ALDH1A1MEN1MAPT | |
| SCHEMBL7712332 | 0.83 | ENPP2 (0.46) | ENPP2HSP90AA1TLR9ALDH1A1MEN1 | |
| SCHEMBL7712325 | 0.83 | ENPP2 (0.46) | ENPP2HSP90AA1TLR9ALDH1A1MEN1 | |
| SCHEMBL14620709 | 0.80 | ENPP2 (0.78) | ENPP2RAD51ALDH1A1MEN1MAPT | |
| SCHEMBL11421159 | 0.80 | ENPP2 (0.78) | ENPP2RAD51ALDH1A1MEN1MAPT | |
| SCHEMBL29673349 | 0.79 | HSP90AA1 (0.43) | ENPP2HSP90AA1ALDH1A1PKMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096874-A1 | COMPOUNDS AND METHODS FOR USING GALLOYLATED POLYPHENOLS TO TREAT DISEASES MEDIATED BY THIOL ISOMERASES | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) | 2025-05-08 | — | — | WO | disclosed |
| US-20250134853-A1 | COMPOUNDS AND METHODS FOR USING GALLOYLATED POLYPHENOLS TO TREAT DISEASES MEDIATED BY THIOL ISOMERASES | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 2025-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250134853-A1 | COMPOUNDS AND METHODS FOR USING GALLOYLATED POLYPHENOLS TO TREAT DISEASES MEDIATED BY THIOL ISOMERASES | GGT1, SPR, PON1 | ENPP2 1452/4885HSP90AA1 222/4885TLR9 4585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.