Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3726823 | 0.88 | IGF1R (0.51) | IGF1R | |
| SCHEMBL17558381 | 0.86 | IGF1R (0.34) | IGF1R | |
| SCHEMBL17558355 | 0.83 | IGF1R (0.35) | IGF1R | |
| SCHEMBL17558364 | 0.83 | IGF1R (0.40) | IGF1R | |
| SCHEMBL2942128 | 0.75 | IGF1R (0.51) | IGF1R | |
| SCHEMBL17558338 | 0.73 | IGF1R (0.31) | IGF1R | |
| SCHEMBL17558367 | 0.72 | IGF1R (0.34) | IGF1R | |
| SCHEMBL3739476 | 0.72 | IGF1R (0.56) | IGF1RTRPV1 | |
| SCHEMBL3726577 | 0.72 | IGF1R (0.56) | IGF1R | |
| SCHEMBL3737325 | 0.72 | IGF1R (0.56) | IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3188729-A1 | CYCLIC UREA COMPOUNDS AS TROPOMYOSIN-RELATED KINASE (TRK) INHIBITORS | Genzyme Corporation (US) | 2017-07-12 | — | — | EP | disclosed |
| WO-2016036796-A1 | CYCLIC UREA COMPOUNDS AS TROPOMYOSIN-RELATED KINASE (TRK) INHIBITORS | GENZYME CORPORATION (US) | 2016-03-10 | — | — | WO | disclosed |