Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CHKA | P35790 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17558828 | 0.92 | ALDH1A1 (0.55) | BCHELIPGACHEKDM4ERAB9A | |
| SCHEMBL19037331 | 0.91 | RAB9A (0.40) | BCHELIPGACHEKDM4ERAB9A | |
| SCHEMBL12972595 | 0.87 | LIPG (0.46) | BCHELIPGACHEKDM4ERAB9A | |
| SCHEMBL21274252 | 0.87 | ESR1 (0.42) | BCHELIPGACHEKDM4ERAB9A | |
| Bromide SCHEMBL30756708 | 0.85 | BCHE (0.42) | BCHELIPGACHEKDM4ERAB9A | |
| SCHEMBL19037337 | 0.83 | ALDH1A1 (0.43) | KDM4ERAB9AALDH1A1MEN1MAPT | |
| SCHEMBL14002932 | 0.83 | ALDH1A1 (0.40) | BCHELIPGACHEKDM4ERAB9A | |
| SCHEMBL19037336 | 0.83 | ALDH1A1 (0.40) | BCHELIPGACHEKDM4ERAB9A | |
| SCHEMBL17558827 | 0.82 | BCHE (0.38) | BCHELIPGACHEKDM4ERAB9A | |
| SCHEMBL19418875 | 0.80 | BCHE (0.67) | BCHEACHECYP2D6HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170285038-A1 | FLUORESCENCE ASSAY FOR INTESTINAL PERMEABILITY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-10-05 | — | — | US | claimed |
| WO-2016036887-A1 | FLUORESCENCE ASSAY FOR INTESTINAL PERMEABILITY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-03-10 | — | — | WO | claimed |
| US-20170285038-A1 | FLUORESCENCE ASSAY FOR INTESTINAL PERMEABILITY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-10-05 | — | — | US | disclosed |
| WO-2016036887-A1 | FLUORESCENCE ASSAY FOR INTESTINAL PERMEABILITY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-03-10 | — | — | WO | disclosed |