Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 6/20 | 0.38 |
| ▸ | PEPD | P12955 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17560404 | 0.95 | SMN1; SMN2 (0.40) | ALDH1A1MAPTSMN1; SMN2KDM4EKDM4C | |
| Hydrochloric Acid SCHEMBL17560460 | 0.93 | SMN1; SMN2 (0.39) | ALDH1A1MAPTSMN1; SMN2KDM4EKDM4C | |
| SCHEMBL16067903 | 0.86 | SMN1; SMN2 (0.49) | ALDH1A1MAPTSMN1; SMN2KDM4EKDM4C | |
| SCHEMBL18884425 | 0.86 | SMN1; SMN2 (0.49) | ALDH1A1MAPTSMN1; SMN2KDM4EKDM4C | |
| SCHEMBL4737546 | 0.80 | POLB (0.47) | ALDH1A1MAPTSMN1; SMN2FKBP1APEPD | |
| SCHEMBL8199687 | 0.80 | POLB (0.47) | ALDH1A1MAPTSMN1; SMN2FKBP1APEPD | |
| SCHEMBL16200561 | 0.77 | MAPT (0.40) | ALDH1A1MAPTSMN1; SMN2KDM4EKDM4C | |
| SCHEMBL694642 | 0.75 | ALDH1A1 (0.40) | ALDH1A1MAPTSMN1; SMN2FKBP1A | |
| SCHEMBL7313171 | 0.75 | FKBP1A (0.54) | ALDH1A1MAPTSMN1; SMN2KDM4EFKBP1A | |
| SCHEMBL8560270 | 0.72 | ALDH1A1 (0.42) | ALDH1A1MAPTSMN1; SMN2KDM4EKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021026803-A1 | PIPERIDINYL-METHYL-PURINEAMINES AS NSD2 INHIBITORS AND ANTI-CANCER AGENTS | NOVARTIS AG (CH) | 2021-02-18 | — | — | WO | disclosed |