Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | GUSB | P08236 | 2/20 | 0.43 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17560756 | 1.00 | LMNA (0.47) | LMNARAB9AMAPTCYP1A2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL19434705 | 0.98 | LMNA (0.46) | LMNARAB9AMAPTCYP1A2SMN1; SMN2 | |
| SCHEMBL17574338 | 0.93 | SMN1; SMN2 (0.46) | LMNARAB9AMAPTCYP1A2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL17560776 | 0.92 | SMN1; SMN2 (0.45) | LMNARAB9AMAPTCYP1A2SMN1; SMN2 | |
| SCHEMBL11877435 | 0.88 | LMNA (0.45) | LMNARAB9AMAPTCYP1A2SMN1; SMN2 | |
| SCHEMBL17560971 | 0.88 | LMNA (0.45) | LMNARAB9AMAPTCYP1A2SMN1; SMN2 | |
| SCHEMBL17598764 | 0.86 | LMNA (0.46) | LMNARAB9AMAPTCYP1A2SMN1; SMN2 | |
| SCHEMBL19449699 | 0.83 | CYP1A2 (0.57) | LMNARAB9AMAPTCYP1A2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL17560953 | 0.82 | CYP1A2 (0.56) | LMNARAB9AMAPTCYP1A2SMN1; SMN2 | |
| SCHEMBL19449850 | 0.82 | MEN1 (0.49) | LMNARAB9AMAPTCYP1A2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3188722-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | Neoculi Pty Ltd (AU) | 2017-07-12 | — | — | EP | claimed |
| WO-2016033635-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | NEOCULI PTY LTD (AU) | 2016-03-10 | — | — | WO | claimed |