Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | GUSB | P08236 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17560776 | 0.99 | SMN1; SMN2 (0.45) | SMN1; SMN2NPC1ATMLMNAGUSB | |
| SCHEMBL17560756 | 0.93 | LMNA (0.47) | SMN1; SMN2NPC1LMNAGUSBRAB9A | |
| SCHEMBL17560757 | 0.93 | LMNA (0.47) | SMN1; SMN2NPC1LMNAGUSBRAB9A | |
| Hydrochloric Acid SCHEMBL19434705 | 0.91 | LMNA (0.46) | SMN1; SMN2NPC1LMNAGUSBRAB9A | |
| SCHEMBL17574293 | 0.87 | LMNA (0.44) | SMN1; SMN2NPC1LMNARAB9ACYP1A2 | |
| Hydrochloric Acid SCHEMBL17560871 | 0.86 | LMNA (0.43) | SMN1; SMN2NPC1LMNARAB9ACYP1A2 | |
| SCHEMBL17574294 | 0.86 | MAOB (0.51) | SMN1; SMN2NPC1LMNAGUSBRAB9A | |
| SCHEMBL16224323 | 0.86 | LMNA (0.53) | SMN1; SMN2NPC1ATMLMNAGUSB | |
| SCHEMBL24278523 | 0.85 | SMN1; SMN2 (0.40) | SMN1; SMN2NPC1ATMLMNARAB9A | |
| Hydrochloric Acid SCHEMBL17560978 | 0.85 | MAOB (0.50) | SMN1; SMN2NPC1LMNAGUSBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11566012-B2 | Methods for treating protozoan infections | NEOCULI PTY LTD (AU) | 2023-01-31 | — | — | US | disclosed |
| EP-3960729-A1 | COMPOUNDS AND METHODS OF TREATING INFECTIONS | Neoculi Pty Ltd (AU) | 2022-03-02 | — | — | EP | disclosed |
| EP-2991968-B1 | COMPOUNDS AND METHODS OF TREATING INFECTIONS | NEOCULI PTY LTD (AU) | 2021-11-10 | — | — | EP | disclosed |
| EP-3188722-B1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | NEOCULI PTY LTD (AU) | 2021-08-04 | — | — | EP | disclosed |
| US-20210009552-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | NEOCULI PTY LTD (AU) | 2021-01-14 | — | — | US | disclosed |
| US-10829468-B2 | Methods for treating protozoan infections | NEOCULI PTY LTD. (AU) | 2020-11-10 | — | — | US | disclosed |
| US-20200290990-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | NEOCULI PTY LTD (AU) | 2020-09-17 | — | — | US | disclosed |
| US-10752606-B2 | Methods for treating protozoan infections | NEOCULI PTY LTD. (AU) | 2020-08-25 | — | — | US | disclosed |
| US-20200102287-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | NEOCULI PTY LTD (AU) | 2020-04-02 | — | — | US | disclosed |
| US-10562880-B2 | Methods for treating protozoan infections | NEOCULI PTY LTD. (AU) | 2020-02-18 | — | — | US | disclosed |
| US-20190330178-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | NEOCULI PTY LTD (AU) | 2019-10-31 | — | — | US | disclosed |
| US-10392363-B2 | Methods for treating protozoan infections | NEOCULI PTY LTD. (AU) | 2019-08-27 | — | — | US | disclosed |
| US-10370341-B2 | Compounds and methods of treating infections | NEOCULI PTY LTD (AU) | 2019-08-06 | — | — | US | disclosed |
| US-10253002-B2 | Compounds and methods of treating infections | NEOCULI PTY LTD (AU) | 2019-04-09 | — | — | US | disclosed |
| US-20190084941-A1 | COMPOUNDS AND METHODS OF TREATING INFECTIONS | NEOCULI PTY LTD (AU) | 2019-03-21 | — | — | US | disclosed |
| US-20170291886-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | NEOCULI PTY LTD (AU) | 2017-10-12 | — | — | US | disclosed |
| WO-2016033635-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | NEOCULI PTY LTD (AU) | 2016-03-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190084941-A1 | COMPOUNDS AND METHODS OF TREATING INFECTIONS | ELANE, IL1A, IL1B | SMN1; SMN2 3440/4885NPC1 813/4885ATM 3995/4885 |
| US-11566012-B2 | Methods for treating protozoan infections | DPM1, ABCB11, PIGS | SMN1; SMN2 3002/4885NPC1 282/4885ATM 4811/4885 |
| US-20200290990-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | DPM1, ABCB11, PIGS | SMN1; SMN2 3002/4885NPC1 282/4885ATM 4811/4885 |
| US-10370341-B2 | Compounds and methods of treating infections | ELANE, IL1A, IL1B | SMN1; SMN2 3440/4885NPC1 813/4885ATM 3995/4885 |
| US-20210009552-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | DPM1, ABCB11, PIGS | SMN1; SMN2 3002/4885NPC1 282/4885ATM 4811/4885 |
| US-20170291886-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | DPM1, ABCB11, PIGS | SMN1; SMN2 3002/4885NPC1 282/4885ATM 4811/4885 |
| US-20200102287-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | DPM1, ABCB11, PIGS | SMN1; SMN2 3002/4885NPC1 282/4885ATM 4811/4885 |
| US-20190330178-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | DPM1, ABCB11, PIGS | SMN1; SMN2 3002/4885NPC1 282/4885ATM 4811/4885 |
| US-10829468-B2 | Methods for treating protozoan infections | DPM1, ABCB11, PIGS | SMN1; SMN2 3002/4885NPC1 282/4885ATM 4811/4885 |
| US-10562880-B2 | Methods for treating protozoan infections | DPM1, ABCB11, PIGS | SMN1; SMN2 3002/4885NPC1 282/4885ATM 4811/4885 |
| US-10752606-B2 | Methods for treating protozoan infections | DPM1, ABCB11, PIGS | SMN1; SMN2 3002/4885NPC1 282/4885ATM 4811/4885 |
| US-10392363-B2 | Methods for treating protozoan infections | DPM1, ABCB11, PIGS | SMN1; SMN2 3002/4885NPC1 282/4885ATM 4811/4885 |
| US-10253002-B2 | Compounds and methods of treating infections | ELANE, IL1A, IL1B | SMN1; SMN2 3440/4885NPC1 813/4885ATM 3995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.