Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11877435 | 1.00 | LMNA (0.45) | LMNAMAOBMAPTRAB9ACYP1A2 | |
| Acetic Acid SCHEMBL21519413 | 0.92 | RAB9A (0.46) | LMNAMAOBMAPTRAB9ACYP1A2 | |
| SCHEMBL17560756 | 0.88 | LMNA (0.47) | LMNAMAOBMAPTRAB9ACYP1A2 | |
| SCHEMBL17560757 | 0.88 | LMNA (0.47) | LMNAMAOBMAPTRAB9ACYP1A2 | |
| Hydrochloric Acid SCHEMBL19434705 | 0.86 | LMNA (0.46) | LMNAMAOBMAPTRAB9ACYP1A2 | |
| SCHEMBL4100069 | 0.84 | MAPT (0.55) | LMNAMAPTRAB9ACYP1A2CYP2C19 | |
| SCHEMBL4100068 | 0.84 | MAPT (0.55) | LMNAMAPTRAB9ACYP1A2CYP2C19 | |
| SCHEMBL31105576 | 0.84 | MAPT (0.58) | LMNAMAOBMAPTRAB9ACYP1A2 | |
| SCHEMBL17044509 | 0.84 | MAPT (0.58) | LMNAMAOBMAPTRAB9ACYP1A2 | |
| SCHEMBL17044511 | 0.84 | MAPT (0.58) | LMNAMAOBMAPTRAB9ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170291886-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | NEOCULI PTY LTD (AU) | 2017-10-12 | — | — | US | claimed |
| EP-3188722-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | Neoculi Pty Ltd (AU) | 2017-07-12 | — | — | EP | claimed |
| WO-2016033635-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | NEOCULI PTY LTD (AU) | 2016-03-10 | — | — | WO | claimed |
| EP-3188722-B1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | NEOCULI PTY LTD (AU) | 2021-08-04 | — | — | EP | disclosed |
| US-20190330157-A1 | THERAPEUTIC COMPOUNDS | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2019-10-31 | — | — | US | disclosed |
| US-20170291886-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | NEOCULI PTY LTD (AU) | 2017-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190330157-A1 | THERAPEUTIC COMPOUNDS | OPRL1, INA, OGFR | LMNA 1901/4885MAOB 1217/4885MAPT 3826/4885 |
| US-20170291886-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | DPM1, ABCB11, PIGS | LMNA 2337/4885MAOB 1831/4885MAPT 3694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.