Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.35 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3031232 | 0.83 | TP53 (0.44) | TP53TDP1PYCR1TAAR1RAB9A | |
| SCHEMBL10456035 | 0.79 | TP53 (0.41) | TP53TDP1PYCR1TAAR1RAB9A | |
| SCHEMBL4050941 | 0.79 | NPC1 (0.45) | TP53TDP1PYCR1RAB9ANPC1 | |
| SCHEMBL9268651 | 0.78 | NPC1 (0.44) | TP53TDP1PYCR1TAAR1RAB9A | |
| SCHEMBL4681634 | 0.78 | NPC1 (0.44) | TP53TDP1PYCR1TAAR1RAB9A | |
| SCHEMBL14729157 | 0.77 | NPC1 (0.46) | TP53TDP1PYCR1TAAR1RAB9A | |
| SCHEMBL9729608 | 0.76 | KDM4E (0.46) | TP53TDP1PYCR1TAAR1RAB9A | |
| SCHEMBL1257786 | 0.75 | NPSR1 (0.45) | TP53TDP1PYCR1TAAR1RAB9A | |
| SCHEMBL9268656 | 0.75 | RAB9A (0.41) | TP53TDP1PYCR1TAAR1RAB9A | |
| SCHEMBL1257788 | 0.75 | SRC (0.62) | RAB9ANPC1KDM4EALDH1A1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9278922-B2 | Anti-viral compounds | ABBVIE INC. (US) | 2016-03-08 | — | — | US | disclosed |